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Table 5 The univariate and multiple meta-regression analysis on the determinant heterogeneity in effect of iron therapy on depression

From: The global prevalence of gastric cancer in Helicobacter pylori-infected individuals: a systematic review and meta-analysis

Variables

Univariate meta-regression

Multiple meta-regression

Coefficient (95% CI)

p-value

R2-adj

Coefficient (95% CI)

p-value

R2-adj

Publication time (yrs.)

0.43 (-0.53 to 1.39)

0.382

0.1%

Not included

–-

13.63%

Continents (score)

1.60 (-2.43 to 5.63)

0.433

0.02%

Not included

–-

Age mean (yrs.)

0.59 (0.15 to 1.03)

0.009

6.96%

0.66 (0.24 to 1.08)

0.003

Sample size (number)

-0.01 (-0.02 to -0.01)

0.003

5.41%

0.-01 (-0.2 to 0.01)

0.84

Study design (score)

3.72 (0.73 to 6.71)

0.015

3.49%

3.08 (-0.92 to 7.08)

0.130

  1. CI Confidence Interval, Coding of study design: 1 = Retrospective cohort; 2 = Prospective cohort; 3 = Retrospective case-series; 4 = Cross sectional; 5 = Prospective case-series
  2. Coding of study continent: 1 = Africa; 2 = America; 3 = Asia; 4 = Europa
  3. *Significant at 0.05