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Table 2 Comparison of characteristics of Persistent BSIs and No persistent BSIs

From: The effect of follow-up blood cultures on mortality and antibiotic use in gram-negative bloodstream infections

 

Persistent (n = 45)

No persistent BSI

(n = 519)

P value

Age, median (IQR)

60 (46–74)

64 (55–76)

0.130

Male sex, n (%)

25 (55.6)

294 (56.69

0.887

CCI (n), median (IQR)

4 (2–6)

5 (3–7)

0.152

SOFA, median (IQR)

4 (1–8)

4 (2–6)

0.014

SIRS, median (IQR)

2 (1–2)

2 (1–3)

0.493

ICU, n (%)

22 (48.9)

207 (39.9)

0.238

Central venous catheter, n (%)

29 (64.4)

220 (42.4)

0.004

Cardiac device, n (%)

6 (13.3)

40 (7.7)

0.186

Prosthetic device, n (%)

1 (2.2)

22 (4.2)

0.512

Hospital-acquired BSI, n (%)

33 (73.3)

297 (57.2)

0.035

Primary BSI, n (%)

16 (35.6)

228 (43.9)

0.277

Secondary BSI, n (%)

29 (64.4)

291 (56.1)

Fermenter GN*, n (%)

20 (44.4)

362 (69.7)

0.001

Non-fermenter GN**, n (%)

25 (55.6)

157 (30.3)

CR-GN, n (%)

16 (48.5)

114 (23.7)

0.002

MDR, n (%)

35 (77.8)

356 (68.6)

0.200

XDR, n (%)

10 (22.2)

66 (12.7)

0.073

PDR, n (%)

1 (2.2)

5 (1.0)

0.430

Appropriate empirical antibiotic therapy, n (%)

10 (22.2)

307 (59.2)

< 0.001

  1. Abbreviations: FUBC: follow-up blood culture, ICU: intensive care unit, IQR: interquartile range, SOFA score: the sequential organ failure assessment score, SIRS: systemic inflammatory response syndrome, BSI: bloodstream infection, CR-GN: carbapenem-resistant gram-negative, MDR: multi-drug resistant, XDR: extensively drug-resistant, PDR: pan-drug resistant
  2. * Escherichia coli (n=173), Klebsiella spp. (n=142), Enterobacter spp. (n=35), Serratia spp. (n=8), Proteus spp. (n=7), Salmonella spp. (n=5), Citrobacter spp. (n=2),Morganella spp. (n=5), Raoultella ornithinolytica (n=2), Aeromonas spp. (n=3)
  3. ** Achromobacter spp. (n=5), Acinetobacter baumannii (n=50), Brucella spp. (n=5), Burkholderia cepacia (n=8), Delftia acidovorans (n=5), Moraxella catarrhalis (n=2), Ochrobactrum anthropi (n=1), Pseudomonas aureginosa (n=37), Pantoea agglomerans (n=2), Ralstonia insidiosa (n=19), Shewanella spp. (n=3), Sphingomonas spp. (n=1), Stenotrophomonas maltophlia (n=44)