Fig. 3
From: Highly sensitive and rapid point-of-care testing for HIV-1 infection based on CRISPR-Cas13a system
ERASE lateral flow strip for CRISPR-based detection. Schematic of the ERASE lateral flow strip for CRISPR-based detection. Gold-labeled FAM-biotinylated reporter molecules flow to the test capture band, and redundant gold nanoparticles flow to the control capture band. Upon recognition of the target RNA, the crRNA/Cas13a complex cleaves to the reporter molecule, allowing passage by the test band