Fig. 5
From: Mitochondrial disturbance related to increased caspase-1 of CD4+T cells in HIV-1 infection
Increased mitochondrial fusion characterizes naive CD4+ T cells from HIV-1 infected patients, and MFN1 is related to the increased MM. (A) Significantly increased MFN1, MFN2 and OPA1 expression in naive CD4+T cells was found in the HD, UNT and ART. (B) The correlations among the levels of mRNA expression of three mitochondrial fusion genes (MFN1, MFN2, and OPA1). (C) Significant correlation was found between the MFI of MM and MFN1 expression in naive CD4+T cells from HIV patients regardless of whether under ART (n = 28), but this was not found for MFN2 and OPA1.