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Table 3 Prevalence of non-TB abnormalities on digital CXR with high CAD scores

From: Assessment of non-tuberculosis abnormalities on digital chest x-rays with high CAD4TB scores from a tuberculosis prevalence survey in Zambia and South Africa

Category of non-TB abnormalities

Non-TB abnormality based on radiological diagnosis

Prevalence % (95% CI)

Only Reader 1 (discordant)

Only Reader 2 (discordant)

Both readers Agreed

Lung parenchyma

Pneumonia not typical of PTB

6.7 (4.7–9.2)

5.2 (3.4–7.4)

2.7 (1.5–4.4)

Chronic scarring/volume loss, likely not related to TB

6.3 (4.4–8.7)

1.1 (0.4–2.5)

2.1 (1.1–3.7)

Mass/nodules: probably malignant/benign

6.3 (4.4–8.7)

1.1 (0.4–2.5)

2.1 (1.1–3.7)

Interstitial pattern, other than edema

7.2 (5.2–9.8)

2.5 (1.3–4.2)

1.5 (0.7–3.0)

Interstitial pattern from cardiac failure

3.8 (2.3–5.8)

1 (0.3–2.2)

1.3 (0.5–2.7)

Suspected Emphysema / Asthma

1.7 (0.8–3.2)

1.1 (0.4–2.5)

1.1 (0.4–2.5)

Non-TB mycobacterial infection

1 (0.3–2.2)

1.7 (0.8–3.2)

1 (0.3–2.2)

Bronchiectasis

2.1 (1.1–3.7)

2.7 (1.5–4.4)

0.6 (0.1–1.7)

Pulmonary edema

1 (0.3–2.2)

1 (0.3–2.2)

0.6 (0.1–1.7)

Broncho vascular inflammation, COPD/ Smoking type

0.4 (0.5–1.4)

1.3 (0.5–2.7)

0.6 (0.1–1.7)

Non-specific opacification

2.7 (1.5–4.4)

2.9 (1.6–4.7

0.4 (0.5–1.4)

Suspected Kaposi sarcoma

1.1 (0.4–2.5)

0.4 (0.5–1.4)

0.2 (0.05–1.1)

Progressive mass fibrosis

0.4 (0.5–1.4)

0

0

Atelectasis

0.2 (0.05–1.1)

0

0

Silicosis

0.2 (0.05–1.1)

0

0

Post radiation fibrosis

0.2 (0.05–1.1)

0

0

Pleura

Pleural effusion/thickening/calcification

11.8 (9.2–14.9)

25.9 (22.2–29.8)

8.8 (6.5–11.5)

Pleural thickening/calcification: likely benign

7.6 (5.5–10.2)

4.2 (2.6–6.3)

2.7 (1.5–4.4)

Pleural thickening/calcification: likely malignant

1 (0.3–2.2)

0.2 (0.05–1.1)

0

Mediastinum

Mass, indeterminate, Suspected Lymphoma

1.1 (0.4–2.5)

0.4 (0.5–1.4)

0.6 (0.1–1.7)

Spinal/para-spinal pathology

1.5 (0.7–3)

0.4 (0.5–1.4)

0.2 (0.05–1.1)

Heart and great vessels

Cardiomegaly

7.2 (5.2–9.8)

2.9 (1.6–4.7)

5 (3.3–7.2)

Aorta atherosclerosis/elongation

1.1 (0.4–2.5)

6.1 (4.2–8.5)

1 (0.3–2.2)

Cardiac pathology: Other

0.8 (0.2–1.9)

0.6 (0.1–1.7)

0.4 (0.5–1.4)

Pericardial effusion

0.4 (0.5–1.4)

0

0

Pulmonary arterial hypertension (PAH)

0

0.2 (0.05–1.1)

0

  1. % Percentage, CI Confidence interval, TB Tuberculosis, COPD Chronic obstructive pulmonary disease