Variable | Categories | Follow-up 2 | Follow-up 3 | Follow-up 4 | ||||||
---|---|---|---|---|---|---|---|---|---|---|
 |  | OR | 95% CI | p-value | OR | 95% CI | p-value | OR | 95% CI | p-value |
Sex | Male | 0.81 | [0.66; 0.98] | * | 0.97 | [0.82; 1.15] | Â | 0.83 | [0.69; 0.99] | * |
Age (years) | 14–19 | 0.82 | [0.49; 1.37] |  | 0.59 | [0.36; 0.97] | * | 0.61 | [0.36; 1.05] |  |
20–34 | 0.59 | [0.45; 0.76] | *** | 0.55 | [0.43; 0.69] | *** | 0.62 | [0.49; 0.78] | *** | |
35–49 | 0.86 | [0.67; 1.11] |  | 1.02 | [0.81; 1.30] |  | 0.89 | [0.70; 1.15] |  | |
50–64 | 1.47 | [1.15; 1.88] | ** | 1.41 | [1.13; 1.76] | ** | 1.57 | [1.24; 1.98] | *** | |
65–79 | 1.87 | [1.36; 2.58] | *** | 2.01 | [1.46; 2.75] | *** | 1.28 | [0.95; 1.71] |  | |
80 +  | 0.88 | [0.57; 1.35] |  | 1.06 | [0.69; 1.63] |  | 1.48 | [0.96; 2.28] |  | |
Birth country | Not Germany | 0.98 | [0.76; 1.27] | Â | 0.59 | [0.47; 0.74] | *** | 0.63 | [0.50; 0.79] | *** |
Level of education | In school | 1.00 | [0.58; 1.73] | Â | 0.88 | [0.52; 1.50] | Â | 1.00 | [0.57; 1.76] | Â |
\(<\) 12Â years | 0.94 | [0.69; 1.27] | Â | 1.10 | [0.83; 1.46] | Â | 0.93 | [0.69; 1.24] | Â | |
\(\ge\) 12Â years | 1.06 | [0.78; 1.45] | Â | 1.03 | [0.77; 1.37] | Â | 1.08 | [0.78; 1.48] | Â | |
Employment status | Employed | 1.07 | [0.86; 1.32] | Â | 1.06 | [0.87; 1.30] | Â | 0.98 | [0.78; 1.22] | Â |
Self employed | 0.89 | [0.65; 1.23] | Â | 0.85 | [0.65; 1.11] | Â | 0.90 | [0.68; 1.20] | Â | |
Unemployed | 0.75 | [0.57; 0.99] | * | 1.27 | [1.00; 1.62] | Â | 1.18 | [0.90; 1.54] | Â | |
Others | 1.40 | [0.84; 2.32] | Â | 0.87 | [0.58; 1.31] | Â | 0.96 | [0.59; 1.58] | Â | |
Risk employment | Yes | 0.85 | [0.63; 1.14] | Â | 1.10 | [0.86; 1.41] | Â | 1.05 | [0.82; 1.34] | Â |
Smoking status | Non smoker | 1.00 | [0.87; 1.16] | Â | 1.17 | [1.03; 1.33] | * | 0.96 | [0.84; 1.09] | Â |
Past smoker | 0.92 | [0.78; 1.09] | Â | 1.01 | [0.87; 1.19] | Â | 1.00 | [0.87; 1.15] | Â | |
Current smoker | 1.08 | [0.91; 1.29] | Â | 0.84 | [0.72; 0.98] | * | 1.05 | [0.89; 1.23] | Â | |
General health | Not good | 0.61 | [0.42; 0.88] | ** | 0.84 | [0.60; 1.18] | Â | 0.59 | [0.41; 0.85] | ** |
Good | 0.92 | [0.73; 1.15] | Â | 1.08 | [0.91; 1.28] | Â | 0.90 | [0.75; 1.08] | Â | |
Very good | 1.28 | [1.05; 1.54] | * | 1.03 | [0.88; 1.21] | Â | 1.19 | [0.99; 1.44] | Â | |
Excellent | 1.39 | [1.11; 1.76] | ** | 1.07 | [0.86; 1.33] | Â | 1.57 | [1.25; 1.97] | *** | |
Respiratory allergies | Yes | 0.92 | [0.71; 1.19] | Â | 1.39 | [1.10; 1.74] | ** | 0.83 | [0.67; 1.02] | Â |
Diabetes | Yes | 1.37 | [0.83; 2.28] | Â | 0.78 | [0.48; 1.29] | Â | 0.81 | [0.51; 1.30] | Â |
CVD | Yes | 1.10 | [0.75; 1.60] | Â | 1.16 | [0.87; 1.54] | Â | 1.15 | [0.83; 1.58] | Â |
Obesity | Yes | 0.86 | [0.50; 1.50] | Â | 0.89 | [0.60; 1.31] | Â | 1.01 | [0.67; 1.51] | Â |
Cancer | Yes | 0.87 | [0.53; 1.43] | Â | 0.98 | [0.58; 1.67] | Â | 1.02 | [0.64; 1.63] | Â |
Lung disease | Yes | 0.93 | [0.59; 1.45] | Â | 0.81 | [0.58; 1.14] | Â | 0.97 | [0.69; 1.36] | Â |
Skin allergies | Yes | 1.12 | [0.81; 1.55] | Â | 0.98 | [0.76; 1.27] | Â | 1.18 | [0.90; 1.54] | Â |
Autoimmune disease | Yes | 1.28 | [0.74; 2.22] | Â | 0.97 | [0.68; 1.40] | Â | 1.34 | [0.86; 2.08] | Â |
Household type | Single | 1.23 | [0.93; 1.62] | Â | 1.25 | [0.96; 1.62] | Â | 0.94 | [0.73; 1.21] | Â |
Couple | 1.24 | [1.03; 1.49] | * | 1.10 | [0.94; 1.29] | Â | 1.19 | [1.01; 1.40] | * | |
Family | 0.85 | [0.69; 1.06] | Â | 0.86 | [0.70; 1.06] | Â | 0.89 | [0.73; 1.10] | Â | |
Others | 0.77 | [0.61; 0.98] | * | 0.85 | [0.68; 1.06] | Â | 1.00 | [0.78; 1.29] | Â | |
Household income (Euro) |  ≤ 2500 | 0.84 | [0.67; 1.05] |  | 0.81 | [0.63; 1.04] |  | 0.94 | [0.75; 1.17] |  |
2501–4000 | 1.01 | [0.78; 1.30] |  | 0.91 | [0.76; 1.10] |  | 0.92 | [0.78; 1.08] |  | |
4001–6000 | 1.13 | [0.95; 1.33] |  | 1.16 | [0.92; 1.46] |  | 1.09 | [0.92; 1.28] |  | |
6001 +  | 1.05 | [0.76; 1.44] |  | 1.16 | [0.94; 1.44] |  | 1.07 | [0.87; 1.32] |  | |
Living area/inhabitant (sqm/individual) |  ≤ 30 | 1.13 | [0.92; 1.38] |  | 0.97 | [0.81; 1.17] |  | 0.96 | [0.80; 1.16] |  |
31–40 | 1.03 | [0.86; 1.23] |  | 0.88 | [0.75; 1.03] |  | 1.02 | [0.86; 1.21] |  | |
41–55 | 0.91 | [0.74; 1.10] |  | 1.27 | [1.06; 1.51] | * | 1.10 | [0.91; 1.33] |  | |
56 +  | 0.95 | [0.74; 1.22] |  | 0.92 | [0.74; 1.15] |  | 0.92 | [0.75; 1.15] |  | |
Building type (nb of apartments) | 1–2 | 1.24 | [1.02; 1.51] | * | 0.90 | [0.76; 1.08] |  | 1.11 | [0.92; 1.33] |  |
3–4 | 0.91 | [0.70; 1.19] |  | 1.48 | [1.14; 1.91] | ** | 1.03 | [0.80; 1.31] |  | |
5 +  | 0.88 | [0.75; 1.04] |  | 0.75 | [0.64; 0.88] | *** | 0.88 | [0.75; 1.03] |  | |
Seropositivity in the previous rounds | Negative | 4.52 | [3.78; 5.40] | *** | 5.42 | [4.74; 6.19] | *** | 5.27 | [4.63; 6.01] | *** |
Positive | 2.01 | [1.48; 2.72] | *** | 1.88 | [1.54; 2.30] | *** | 1.90 | [1.57; 2.31] | *** | |
Missing | 0.11 | [0.09; 0.13] | *** | 0.10 | [0.08; 0.12] | *** | 0.10 | [0.09; 0.12] | *** |