|  | Overall Analysis | Dosing Sub-Analysis | ||||
---|---|---|---|---|---|---|---|
Variables | Total N = 61,124 | Concordant (%) N = 20,014 | Discordant (%) N = 41,110 | Unadjusted Prevalence Ratio (95% CI) | Concordant (%) N = 13,681 | Discordant (%) N = 6,333 | Unadjusted Prevalence Ratio (95% CI) |
Main Independent Variable | |||||||
 Dental Setting | |||||||
  Non-VA | 42,832 (70.1) | 14,351 (71.7) | 28,481 (69.3) | Reference | 9.507 (69.5) | 4,844 (71.4) | Reference |
  VA | 18,292 (29.9) | 5,663 (28.3) | 12,629 (30.7) | 0.92 (0.90–0.95) | 4,174 (30.5) | 1,812 (28.6) | 1.12 (1.08–1.16) |
Demographics & Clinical Characteristics | |||||||
 Mean Age (SD) | 59.1 (10.4) | 56.8 (13.1) | 60.0 (12.0) | 1.00 (0.99–1.00) | 56.7 (14.0) | 56.7 (12.4) | 1.00 (0.99–1.00) |
 Age Group | |||||||
  18–24 | 1,799 (2.9) | 1,550 (7.7) | 249 (0.6) | Reference | 1,155 (8.4) | 395 (8.4) | Reference |
  35–44 | 2,361 (3.9) | 1,430 (7.1) | 931 (2.3) | 0.70 (0.68–0.73) | 952 (7.0) | 478 (7.6) | 0.89 (0.85–0.94) |
  45–54 | 10,382 (17.0) | 3,752 (18.8) | 6,630 (16.1) | 0.42 (0.41–0.43) | 2,522 (18.4) | 1,230 (19.4) | 0.90 (0.87–0.94) |
  55–64 | 33,641 (55.0) | 8,992 (43.9) | 24,649 (60.0) | 0.31 (0.30–0.32) | 5,890 (43.1) | 3,102 (49.0) | 0.88 (0.85–0.91) |
  65 +  | 12,941 (21.2) | 34,290 (22.4) | 8.651 (21.0) | 0.38 (0.37–0.40) | 3,162 (23.1) | 1,128 (17.8) | 0.99 (0.96–1.02) |
 Sex | |||||||
  Male | 37,253 (61.0) | 12.366 (61.8) | 24,887 (60.5) | Reference | 8,747 (63.9) | 3,619 (57.2) | Reference |
  Female | 23,871 (39.0) | 7,648 (38.2) | 16,223 (39.5) | 0.97 (0.94–0.99) | 4,934 (36.1) | 2,714 (428) | 0.91 (0.89–0.93) |
 Cardiac Condition or Prosthetic Joint | |||||||
  Cardiac Condition | 15,707 (25.7) | 14,107 (70.5) | 1,600 (3.9) | Reference | 9,586 (70.1) | 4,521 (71.4) | Reference |
  Prosthetic Joint | 38,445 (62.9) | 0 (0.0) | 38,445 (93.5) | – | – | – | – |
  Both | 6,972 (11.4) | 5,907 (29.5) | 1,065 (2.6) | 0.94 (0.93–0.95) | 4,095 (29.9) | 1,812 (28.6) | 1.02 (0.99–1.04) |
 Region | |||||||
  Northeast | 7,901 (12.9) | 2,915 (14.6) | 4,986 (12.1) | Reference | 1,864 (13.6) | 1,051 (16.6) | Reference |
  Midwest | 22,780 (37.3) | 6,893 (34.4) | 15,887 (38.7) | 0.82 (0.79–0.85) | 2,998 (36.5) | 1,895 (29.9) | 1.13 (1.10–1.17) |
  South | 22,635 (37.0) | 7,766 (38.8) | 14,869 (36.2) | 0.93 (0.90–0.96) | 5,268 (38.5) | 2,498 (39.4) | 1.06 (1.03–1.09) |
  West | 7,808 (12.8) | 2,440 (12.2) | 5,368 (13.0) | 0.85 (0.81–0.88) | 1,551 (11.3) | 889 (14.0) | 0.99 (0.95–1.04) |
 Location | |||||||
  Rural | 9,659 (15.8) | 2,829 (14.1) | 6,830 (16.6) | Reference | 2,181 (15.9) | 648 (10.2) | Reference |
  Urban | 51,465 (84.2) | 17,185 (85.9) | 34,280 (83.4) | 1.14 (1.10–1.18) | 11,500 (84.1) | 5,685 (89.8) | 0.87 (0.85–0.89) |
 Year | |||||||
  2015 | 20,684 (33.8) | 6,684 (33.4) | 14,000 (34.1) | Reference | 4,594 (33.6) | 2,090 (33.0) | Reference |
  2016 | 20,745 (22.9) | 6,803 (34.0) | 13,942 (33.9) | 1.01 (0.99–1.04) | 2,641 (33.9) | 2,162 (34.1) | 0.99 (0.97–1.12) |
  2017 | 19,695 (32.3) | 6,527 (32.6) | 13,168 (32.0) | 1.03 (0.98–1.05) | 4,446 (32.5) | 2,081 (32.9) | 0.99 (0.97–1.01) |
Comorbidities | |||||||
 Mean Charlson (SD) | 0.91 (1.5) | 1.2 (1.3) | 0.75 (1.8) | 1.21 (1.20–1.22) | 1.23 (1.8) | 1.22 (1.8) | 1.00 (0.99–1.01) |
 Myocardial Infarction | |||||||
  No | 60,217 (98.5) | 19,437 (97.2) | 40,780 (99.2) | Reference | 13,300 (97.2) | 6,137 (96.9) | Reference |
  Yes | 907 (1.5) | 577 (2.8) | 330 (0.8) | 1.97 (1.87–2.07) | 381 (2.8) | 196 (3.1) | 0.96 (0.91–1.02) |
 Congestive Heart Failure | |||||||
  No | 56,315 (92.1) | 16,633 (83.1) | 39,682 (96.5) | Reference | 11,311 (82.7) | 5,322 (84.0) | Reference |
  Yes | 4,809 (7.9) | 3,381 (16.9) | 1,428 (3.5) | 2.38 (2.33–2.43) | 2,370 (17.3) | 1,011 (16.0) | 1.03 (1.01–1.06) |
 Peripheral Vascular Disease | |||||||
  No | 57,330 (93.8) | 17,856 (89.2) | 29,474 (96.0) | Reference | 12,197 (89.2) | 5,659 (89.4) | Reference |
  Yes | 3,794 (6.2) | 2,158 (10.8) | 1,636 (4.0) | 1.83 (1.77–1.88) | 1,484 (10.8) | 674 (10.6) | 1.01 (0.98–1.04) |
 Cerebrovascular Disease | |||||||
  No | 58,824 (96.2) | 18,611 (93.0) | 40,213 (97.8) | Reference | 12,725 (93.0) | 5,886 (92.9) | Reference |
  Yes | 2,300 (3.8) | 1,403 (7.0) | 897 (2.2) | 1.93 (1.86–2.00) | 956 (7.0) | 447 (7.1) | 00.99 (0.96–1.03) |
 Dementia | |||||||
  No | 60,811 (99.5) | 19.852 (99.2) | 40,959 (99.6) | Reference | 13,558 (99.1) | 6,294 (99.4) | Reference |
  Yes | 313 (0.5) | 162 (0.8) | 151 (0.4) | 1.59 (1.42–1.76) | 123 (0.9) | 39 (0.6) | 1.11 (1.02–1.21) |
 COPD | |||||||
  No | 53,515 (87.6) | 17,160 (85.7) | 36,355 (88.4) | Reference | 11,751 (85.9) | 5,409 (85.4) | Reference |
  Yes | 7,609 (12.4) | 2,854 (14.3) | 4,755 (11.6) | 1.17 (1.13–1.21) | 1,930 (14.1) | 924 (14.6) | 0.99 (0.96–1.01) |
 Connective Tissue Disease | |||||||
  No | 59,172 (96.8) | 19,427 (97.1) | 39,745 (96.7) | Reference | 13,288 (97.1) | 6,139 (96.9) | Reference |
  Yes | 1,952 (3.2) | 587 (2.9) | 1,365 (3.3) | 0.92 (0.86–0.98) | 393 (2.9) | 194 (3.1) | 0.98 (0.92–1.04) |
 Peptic Ulcer Disease | |||||||
  No | 60,657 (99.2) | 19,832 (99.1) | 40,825 (99.3) | Reference | 13,553 (99.1) | 6,279 (99.2) | Reference |
  Yes | 467 (0.8) | 182 (0.9) | 285 (0.7) | 1.19 (1.06–1.34) | 128 (0.9) | 54 (0.8) | 1.03 (0.94–1.13) |
 Liver Disease | |||||||
  No | 59,063 (96.6) | 19,182 (95.8) | 39,881 (97.0) | Reference | 13.150 (96.1) | 6,032 (95.3) | Reference |
  Mild | 1,534 (2.5) | 582 (2.9) | 952 (2.3) | 1.17 (1.09–1.25) | 358 (2.6) | 224 (3.5) | 0.90 (0.84–0.96) |
  Moderate to Severe | 527 (0.9) | 250 (1.3) | 277 (0.7) | 1.46 (1.33–1.60) | 173 (1.3) | 77 (1.2) | 1.91 (0.93–1.10) |
 Diabetes | |||||||
  No | 51.932 (85.0) | 16,942 (84.6) | 34,990 (85.1) | Reference | 11,600 (84.8) | 5,342 (84.4) | Reference |
  Uncomplicated | 6,880 (11.3) | 2,132 (10.7) | 4,748 (11.6) | 0.95 (0.92–0.99) | 1,433 (10.5) | 699 (11.0) | 0.98 (0.95–1.02) |
  Complicated | 2,312 (3.7) | 940 (4.7) | 1,372 (3.3) | 1.25 (1.18–1.31) | 648 (4.7) | 292 (4.6) | 1.01 (0.96–1.05) |
 Paraplegia/Hemiplegia | |||||||
  No | 60,826 (99.5) | 19,857 (99.2) | 40,969 (99.7) | Reference | 113,575 (99.2) | 6,282 (99.2) | Reference |
  Yes | 298 (0.5) | 157 (0.8) | 141 (0.3) | 1.61 (1.45–1.80) | 106 (0.8) | 51 (0.8) | 0.99 (0.89–1.10) |
 Renal Disease | |||||||
  No | 56,615 (92.6) | 17,850 (89.2) | 38,765 (94.3) | Reference | 12,161 (88.9) | 5,689 (89.8) | Reference |
  Yes | 4,509 (7.4) | 2,164 (10.8) | 2,345 (5.7) | 1.52 (1.47–1.57) | 1,520 (11.1) | 6444 (10.2) | 1.03 (1.00–1.06) |
 Cancer | |||||||
  No | 57,490 (94.1) | 18,752 (93.7) | 38,738 (94.2) | Reference | 12,818 (93.7) | 5,934 (93.7) | Reference |
  Yes | 3,634 (5.9) | 1,262 (6.3) | 2,372 (5.8) | 1.06 (1.02–1.11) | 863 (6.3) | 399 (6.3) | 1.00 (0.96–1.04) |
 Metastatic Solid Tumor | |||||||
  No | 60,801 (99.5) | 19.889 (99.4) | 40,912 (99.5) | Reference | 13,595 (99.4) | 6,294 (99.4) | Reference |
  Yes | 323 (0.5) | 125 (0.6) | 198 (0.5) | 1.18 (1.03–1.36) | 86 (0.6) | 39 (0.6) | 1.01 (0.89–1.13) |
 AIDS | |||||||
  No | 61,035 (99.9) | 19,977 (99.8) | 41,058 (99.9) | Reference | 13,656 (99.8) | 6,321 (99.8) | Reference |
  Yes | 89 (0.1) | 37 (0.2) | 52 (0.1) | 1.27 (0.99–1.63) | 25 (0.2) | 12 (0.2) | 0.99 (0.79–1.24) |
Dental Procedures | |||||||
 Gingival Manipulation | |||||||
  No | 7,505 (12.3) | 0 (0.0) | 7,505 (18.3) | Reference | –-b | –- | –- |
  Yes | 53,619 (87.7) | 20,014 (100.0) | 33,605 (81.7) | –- | –- | –- | –- |
 Adjunctive | |||||||
  No | 57,368 (93.9) | 19,063 (95.2) | 38.305 (93.2) | Reference | 13,051 (95.4) | 6,012 (94.9) | Reference |
  Yes | 2,756 (6.1) | 951 (4.8) | 2,805 (6.8) | 0.76 (0.72–0.81) | 630 (4.6) | 321 (5.1) | 0.97 (0.92–1.01) |
 Diagnostic | |||||||
  No | 17,585 (28.8) | 4,360 (21.8) | 13.225 (32.2) | Reference | 2,967 (21.7) | 1,393 (22.0) | Reference |
  Yes | 43,539 (72.2) | 15,654 (78.2) | 27.,885 (67.8) | 1.45 (1.41–1.49) | 10.714 (78.3) | 4,940 (78.0) | 1.01 (0.98–1.03) |
 Endodontics | |||||||
  No | 59,690 (97.7) | 19.530 (97.6) | 0.410 | Reference | 13,367 (97.7) | 6,163 (97.3) | Reference |
  Yes | 1,434 (2.3) | 484 (2.4) | 950 (2.3) | 1.04 (0.96–1.11) | 314 (2.3) | 170 (2.7) | 0.95 (0.89–1.01) |
 Implant | |||||||
  No | 60,268 (98.6) | 19.756 (98.8) | 40,512 (98.5) | Reference | 13,520 (98.8) | 6,236 (98.5) | Reference |
  Yes | 856 (1.4) | 258 (1.3) | 598 (1.5) | 0.92 (0.83–1.02) | 161 (1.2) | 97 (1.5) | 0.91 (0.83–1.00) |
 Maxillofacial Prosthetics | |||||||
  No | 61,082 (99.9) | 20,005 (99.9) | 41,077 (99.9) | Reference | 13.675 (99.9) | 6,330 (99.9) | Reference |
  Yes | 42 (0.1) | 9 (0.1) | 33 (0.1) | 0.65 (0.37–1.17) | 6 (0.1) | 3 (0.1) | 0.98 (0.61–1.55) |
 Oral Maxillofacial Surgery | |||||||
  No | 57,435 (94.0) | 18,545 (92.7) | 28,890 (94.6) | Reference | 12,703 (92.8) | 5,842 (92.3) | Reference |
  Yes | 3,689 (6.0) | 1,469 (7.3) | 2,220 (5.4) | 1.23 (1.18–1.29) | 978 (7.2) | 491 (7.8) | 0.97 (0.94–1.01) |
 Orthodontics | |||||||
  No | 61,054 (99.9) | 19,999 (99.9) | 41,055 (99.9) | Reference | 13,670 (99.9) | 6,329 (99.9) | Reference |
  Yes | 70 (0.1) | 15 (0.1) | 55 (0.1) | 0.65 (0.42–1.02) | 11 (0.1) | 4 (0.1) | 1.08 (0.79–1.46) |
 Periodontics | |||||||
  No | 56,376 (92.2) | 18,275 (91.3) | 38,101 (92.7) | Reference | 12,535 (91.6) | 5,740 (90.6) | Reference |
  Yes | 4,748 (7.8) | 1,739 (8.7) | 3,009 (7.3) | 1.13 (1.09–1.18) | 1,146 (8.4) | 593 (9.4) | 0.96 (0.93–1.00) |
 Preventive | |||||||
  No | 31,436 (51.4) | 9,192 (45.9) | 22,244 (54.1) | Reference | 6,334 (46.3) | 2,858 (45.1) | Reference |
  Yes | 29,688 (48.6) | 10,822 (54.1) | 18,866 (45.9) | 1.25 (1.22–1.27) | 7,347 (53.7) | 2,475 (55.9) | 0.99 (0.97–1.00) |
 Prosthodontics | |||||||
  No | 59,060 (96.6) | 19,594 (97.9) | 39,466 (96.0) | Reference | 13,399 (97.9) | 6,195 (97.8) | Reference |
  Yes | 2,064 (3.4) | 420 (2.1) | 1,644 (4.0) | 0.61 (0.56–0.67) | 282 (2.1) | 138 (2.2) | 0.98 (0.91–1.05) |
 Fixed Prosthodontics | |||||||
  No | 60,327 (98.7) | 19,920 (99.5) | 40.407 (98.3) | Reference | 13,617 (99.5) | 6,303 (99.5) | Reference |
  Yes | 797 (1.3) | 94 (0.5) | 703 (1.7) | 0.36 (0.29–0.43) | 64 (0.5) | 30 (0.5) | 1.00 (0.87–1.14) |
 Restorative | |||||||
  No | 46,350 (75.8) | 16,184 (80.7) | 30,202 (73.5) | Reference | 11,047 (80.8) | 5,101 (80.6) | Reference |
  Yes | 14,774 (24.2) | 3.866 (19.3) | 10,908 (26.5) | 0.75 (0.73–0.77) | 2,634 (19.2) | 1,232 (19.4) | 1.00 (0.97–1.02) |
 Uncategorized | |||||||
  No | 60,717 (99.3) | 19,913 (99.5) | 40,804 (99.3) | Reference | 13,607 (99.5) | 6,306 (99.6) | Reference |
  Yes | 407 (0.7) | 101 (0.5) | 306 (0.7) | 0.76 (0.64–0.90) | 74 (0.5) | 27 (0.4) | 1.07 (0.95–1.21) |