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Table 4 Predictors of moderate/severe disease among hospitalized children with COVID-19

From: Risk factors for disease severity among children with Covid-19: a clinical prediction model

 

Univariate Logistic Regression

Multivariate Logistic Regression

OR (95% CI)

p-value

aOR (95% CI)

p-value

Age (years)a

0·94 (0·90 – 0·98)

0·003

0·96 (0·90 – 1·01)

0·10

Presence of any comorbidity

2·79 (1·83 – 4·23)

 < 0·001

2·03 (1·12 – 3·66)

0·02

Fever

1·56 (1·05 – 2·33)

0·03

1·32 (0·75 – 2·35)

0·34

Shortness of breath

25·93 (12·78 – 52·59)

 < 0·001

8·70 (3·43 – 22·06)

 < 0·001

Vomiting

4·82 (3·23 – 7·20)

 < 0·001

3·32 (1·99 – 5·55)

 < 0·001

Diarrhea

3·03 (1·95 – 4·72)

 < 0·001

2·87 (1·61 – 5·09)

 < 0·001

Rash

2·50 (1·20 – 5·24)

0·02

2·58 (1·03 – 6·46)

0·04

Seizures

10·71 (5·11 – 22·45)

 < 0·001

4·47 (1·79 – 11·19)

0·001

Temperature on arrival (°C)a

3·32 (2·74 – 4·04)

 < 0·001

2·88 (2·30 – 3·63)

 < 0·001

Chest recessions

126·87 (30·43 – 529·00)

 < 0·001

28·84 (5·95 – 139·69)

 < 0·001

Abnormal breath sounds

37·58 (11·10 – 127·24)

 < 0·001

5·89 (1·09 – 31·76)

0·04

  1. OR odds ratio, aOR adjusted odds ratio, CI confidence interval
  2. aper 1-unit increase