From: Risk factors for disease severity among children with Covid-19: a clinical prediction model
Mild Disease (n = 1,023) | Moderate/severe Disease (n = 211) | p-value | |
---|---|---|---|
Demography | |||
Age in years, median (IQR) | 3·1 (1·0 – 7·6) | 1·9 (0·7 – 6·2) | < 0·001c |
Male sex | 511 (49·9%) | 121 (57·3%) | 0·05d |
Malay ethnicity | 844 (82·5%) | 183 (86·7%) | 0·09d |
Previous COVID-19 infectiona | 6 (0·6%) | 0 (0%) | 0·60d |
Obesity | 35 (3·4%) | 13 (6·2%) | 0·06d |
Any comorbidities | 77 (7·5%) | 39 (18·5%) | < 0·001d |
Type of Comorbidities | |||
Respiratory | 34 (3·3%) | 11 (5·2%) | 0·18d |
Prematurity (if age < 2 years)b | 21 (2·1%) | 7 (3·3%) | 0·26d |
Cardiovascular | 15 (1·5%) | 9 (4·3%) | 0·01d |
Genetic | 10 (1·0%) | 6 (2·8%) | 0·03d |
Neuromuscular | 7 (0·7%) | 8 (3·8%) | < 0·001d |
Gastrointestinal | 2 (0·2%) | 4 (1·9%) | 0·001e |
Others | 10 (1·0%) | 4 (1·9%) | 0·25d |
Symptoms | |||
Fever | 793 (77·5%) | 178 (84·4%) | 0·03d |
Cough | 419 (41·0%) | 88 (41·7%) | 0·84d |
Rhinorrhea | 377 (36·9%) | 65 (30·8%) | 0·10d |
Sore throat | 36 (3·5%) | 5 (2·4%) | 0·40d |
Shortness of breath | 10 (1·0%) | 43 (20·4%) | < 0·001d |
Vomiting | 65 (6·4%) | 52 (24·6%) | < 0·001d |
Diarrhea | 63 (6·2%) | 35 (16·6%) | < 0·001d |
Seizures | 11 (1·1%) | 22 (10·4%) | < 0·001d |
Rash | 22 (2·2%) | 11 (5·2%) | 0·01d |
Anosmia/ageusia | 44 (4·3%) | 3 (1·4%) | 0·05d |
Physical Findings | |||
Temperature on arrival in ºC, median (IQR) | 36·6 (36·4 – 36·8) | 37·0 (36·8 – 38·0) | < 0·001c |
Chest recessions | 2 (0·2%) | 42 (19·9%) | < 0·001d |
Abnormal breath sounds | 3 (0·3%) | 21 (10·0%) | < 0·001d |