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Table 1 Comparison of the characteristics of the four groups of patients who answered the satisfaction questionnaire

From: Acceptance of diagnosis and management satisfaction of patients with “suspected Lyme borreliosis” after 12 months in a multidisciplinary reference center: a prospective cohort study

Characteristics of the patients

Total

N = 349 (%)

Confirmed LB

N = 48 (%)

Possible LB

N = 31 (%)

PTLDS or sequelae

N = 34 (%)

Other diagnoses

N = 236 (%)

P value

Age, (years), median [IQR]

48 [35,62]

48 [35,62]

49 [35,62]

48 [35,62]

48 [35,61]

0.242

Male

146 (41.8)

30 (62.5)

16 (51.6)

9 (26.5)

91 (38.6)

0.003

Lifestyle

     

0.287

 Home in a rural area

72 (20.6)

6 (12.5)

10 (32.3)

7 (20.6)

49 (20.8)

-

 Employment in rural areas/forest

17 (4.9)

2 (4.2)

1 (3.2)

0 (0.0)

14 (5.9)

-

 Forest-based leisure activities

249 (71.4)

40 (83.3)

20 (64.5)

26 (76.5)

163 (69.1)

-

 No exposure

11 (3.2)

0 (0.0)

0 (0.0)

1 (2.9)

10 (4.2)

-

Past history of tick-bite

234 (67.1)

40 (83.3)

25 (80.7)

28 (82.4)

141 (59.8)

0.001

Past history of erythema migrans

97 (27.9)

29 (60.4)

11 (35.5)

16 (48.5)

41 (17.4)

 < 0.001

Patients referred by a physician

with a letter

313 (89.7)

46 (95.8)

30 (96.8)

30 (88.2)

207 (87.7)

0.108

 General Practitioner

241 (69.1)

31 (64.6)

26 (83.9)

26 (76.5)

158 (67.0)

 

 Specialist physician

59 (16.9)

11 (22.9)

2 (6.5)

4 (11.8)

42 (17.8)

 

 Emergency unit physician

13 (3.7)

4 (8.3)

2 (6.5)

0 (0.0)

7 (3.0)

 

 No letter, patient self-referral

36 (10.3)

2 (4.2)

1 (3.2)

4 (11.8)

29 (12.3)

 

Duration (days) of chief complaints prior to consultation at TBD-RC, median [IQ 25,75]

425.5

[140.5, 1208.5]

406.5

[135, 1171]

422

[139, 1191]

425.5

[144, 1208.5]

532.5

[167.5, 1456.5]

 < 0.001

Patient's chief complaint

     

 < 0.001

 Erythema migrans

10 (2.9)

6 (12.5)

0 (0.0)

1 (2.9)

3 (1.3)

 

 Clinical signs/symptoms evoking early disseminated LB (< 6 months)

100 (28.7)

27 (56.3)

12 (38.7)

10 (29.4)

51 (21.6)

 

 Clinical signs/symptoms evoking late disseminated LB (> 6 months)

232 (66.5)

15 (31.3)

19 (61.3)

23 (67.7)

175 (74.2)

 

 Questions after a tick-bite

4 (1.2)

0 (0.0)

0 (0.0)

0 (0.0)

4 (1.7)

 

 Positive serological test with no clinical signs

3 (0.9)

0 (0.0)

0 (0.0)

0 (0.0)

3 (1.3)

 

Serological test

     

 < 0.001

 IgM and/or IgG positive in ELISA and WB

111 (31.8)

33 (68.8)

12 (38.7)

19 (55.9)

47 (19.9)

 

 IgG positive in ELISA only

46 (13.2)

5 (10.4)

8 (25.8)

5 (14.7)

28 (11.9)

 

 IgM and IgG negative in ELISA

163 (46.7)

7 (14.6)

11 (35.5)

10 (29.4)

135 (57.2)

 

 No serology (suspicion of erythema migrans)

26 (7.5)

3 (6.3)

0 (0.0)

0 (0.0)

23 (9.8)

 

Antibiotic therapy prescribed before TBD-RC

228 (65.3)

36 (75.0)

16 (51.6)

34 (100.0)

142 (60.2)

 < 0.001

 Antibiotic therapy > 4 weeks

71 (20.3)

12 (25.0)

2 (6.5)

14 (41.2)

43 (18.2)

0.003

 Non-recommended treatments (> 8 weeks of antibiotics and/or associated antimicrobials)

61 (17.5)

6 (12.5)

0 (0.0)

10 (29.4)

45 (19.1)

0.011

  1. LB Lyme borreliosis, PTLDS Post-Treatment Lyme Disease Syndrome, IQR Inter quartile range, ELISA Enzyme-Linked Immunosorbent Assay, WB Western-Blot, TBD-RC Tick-Borne Diseases Reference Center