Field evaluation of a point-of-care triage test for active tuberculosis (TriageTB)

BMC Infectious Diseases

Table 1 Study schedule for participants with active TB (Phase 1 and Phase 2)

	Screening/ Enrolment	Day 0^a	Week 4	Week 8	Week 16	Month 6	Unscheduled/ TB Relapse 1	Month 12^c	Unscheduled/ TB Relapse 2	Month 18
Informed consent/assent	X
Eligibility criteria	X
Medical history	X	X	X	X	X	X	X	X	X	X
TB symptoms	X	X	X	X	X	X	X	X	X	X
POC safety tests	X	ICI					ICI		ICI
HIV-1 testing	X
Vital signs/directed physical exam	X	X	X	X	X	X	X	X	X	X
Blood sample	X	X	X	X	X	X
POC FSB tests	X			X	X	X
Urine	X			X	X	X
Sputum	X			X^b	X^b	X^b	ICI	ICI	ICI	ICI
Nasopharyngeal swab	X						ICI		ICI
Chest X-ray	X			ICI		ICI	ICI	ICI	ICI	ICI
Further care provision/referral	ICI	X	ICI	ICI	ICI	ICI	ICI	ICI	ICI	ICI

FSB Fingerstick blood, HIV Human immune-deficiency virus, ICI If clinically indicated, POC Point-of-care
^aTB call-Back
^bMGIT culture only
^cPhone-call ± visit if clinically indicated

ISSN: 1471-2334