COVID-19 vaccine manufacturer | Vaccine Platform | Primary Series Dosing | Booster Dose Guidance, in United States, at time of investigationa | Alternative vaccine names | Anti-spike antibody elicited | Anti-nucleocapsid antibody elicited |
---|---|---|---|---|---|---|
Covaxin | Inactivated, whole virus | 2 doses, 28 days apart | n/a | BBV152 | ✓ | ✓ |
Covishield (AstraZeneca) | Chimp Adenovirus Vector | 2 doses, 28-84 days apart | n/a | ChAdOx1-S [recombinant] | ✓ | |
Johnson & Johnson’s Janssen (J&J/Janssen) | Human Adenovirus Vector | 1 dose | In most situations, Pfizer-BioNTech or Moderna booster are recommended over a J&J /Janssen booster. J&J /Janssen boosters can be considered for: i) those who had a severe reaction to Moderna or Pfizer-BioNTech vaccine ii) those who would otherwise remain unvaccinated due to limited access to Pfizer-BioNTech or Moderna vaccines iii) those who want to get the J&J/Janssen booster despite safety recommendations | AD26.COV2-S | ✓ | |
Moderna | mRNA vaccine | 2 doses, 28 days apart | 1 dose, ≥ 6 months after final dose in primary series (for Moderna and Pfizer-BioNTech recipients) OR ≥ 2 months after vaccination with J&J/Janssen | SpikeVax (mRNA-1273) | ✓ | |
Pfizer-BioNTech | mRNA vaccine | 2 doses, 21 days apart | 1 dose, ≥ 6 months after final dose in primary series (for Moderna and Pfizer-BioNTech recipients) OR ≥ 2 months after vaccination with J&J/Janssen | Comirnaty (BNT162b2) | ✓ | |
Sinopharm | Inactivated, whole virus | 2 doses, 21 days apart | n/a | BIBP | ✓ | ✓ |
Sinovac | Inactivated, whole virus | 2 doses, 14-28 days apart | n/a | CoronaVac | ✓ | ✓ |