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Table 1 The Mantoux and IGRA results of TBM infants

From: Interferon-γ release assay and mantoux response in infants with tuberculous meningitis in low and intermediate burden countries

 

Total

Mantoux results (n)

IGRA (n)

Negative (< 5 mm)

Positive (≥ 5 mm)

Negative, or Indetermine

Positive

Number

48

20

27

2

7

Age (months)

9.4 ± 5.8

8.4 ± 5.9

9.9 ± 5.8

17.0 ± 1.4

12.7 ± 5.4

Sex (male, %)

57.1% (24/42)

42.1% (8/19)

43.5% (10/23)

100% (2/2)

42.9% (3/7)

Microbiological TB evidence

    
 

CNS (-)

22

9

13

0

3

 

CNS (+)

26

11

14

2

4

 

Non-CNS (-)

21

10

10

1

3

 

Non-CNS (+)

27

10

17

1

4

 

Total (-)

13

4

9

0

2

 

Total (+)

35

16

18

2

5

BCG vaccination (n = 36)

    
 

Yes

16

7

8

1

0

 

No

20

8

12

1

6

M.TB (n = 33)

    
 

Yes

32

13

19

1

6

 

No, BCG

1

0

0

1

0

  1. IGRA, Interferon-γ Release Assay; TBM, tuberculous meningitis; TB, tuberculosis; CNS, central nervous system; BCG, Bacille Calmette-Guérin; M.TB, Mycobacterium Tuberculosis