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Table 6 Mortality, ICU admission and related events after propensity score matching

From: Intermediate dose enoxaparin in hospitalized patients with moderate-severe COVID-19: a pilot phase II single-arm study, INHIXACOVID19

 

Interventional cohort

Observational cohort

P-value

N

Median (IQR) or n (%)

N

Median (95% CI) or n (%)

Death within 30 days from heparin onset

88

3 (3.4%)

90

1 (1.1%)

0.37

Cause of death at 30 days

3

 

1

  

 COVID-19

 

2 (66.7%)

 

1 (100.0%)

 

 COVID-19 complications

 

1 (33.3%)

 

0 (0.0%)

 

Death within 90 days from heparin onset

89

3 (3.4%)

90

1 (1.1%)

0.37

Cause of death at 90 days

3

 

1

  

 COVID-19

 

2 (66.7%)

 

1 (100.0%)

 

 COVID-19 complications

 

1 (33.3%)

 

0 (0.0%)

 

Length of hospitalization [days]

85

14 (9, 16)

85

14 (10, 20)

0.08

NIV

90

14 (15.6%)

90

10 (11.1%)

0.51

CPAP

90

11 (12.2%)

90

11 (12.2%)

1.00

High nasal O2 flow

90

16 (17.8%)

90

14 (15.6%)

0.84

ICU admission

90

12 (13.3%)

90

8 (8.9%)

0.48

Length of ICU stay [days]

8

8 (5, 17)

8

6 (5, 10)

0.76

Death within 90 days or ICU admission

89

13 (14.6%)

90

9 (10.0%)

0.37

Improvement of clinical status between visit 1 and visit 3

90

58 (64.4%)

90

52 (57.8%)

0.36