Skip to main content

Table 4 Heparin administration in the interventional and observational cohort

From: Intermediate dose enoxaparin in hospitalized patients with moderate-severe COVID-19: a pilot phase II single-arm study, INHIXACOVID19

 

Interventional cohort

Observational cohort

P-value

N

Median (IQR) or n (%)

N

Median (IQR) or n (%)

Pre-enrolment heparin administration

98

66 (66.0%)

 

n/a

n/a

Dose

64

  

n/a

n/a

 40 mg

 

45 (70.3%)

   

 60 mg

 

10 (15.6%)

   

 80 mg

 

8 (12.5%)

   

 100 mg

 

1 (1.6%)

   

Heparin dosage

98

 

203

 

 < 0.001

 40 mg

 

0 (0.0%)

 

198 (97.5%)

 

 60 mg

 

6 (6.1%)

 

2 (1.0%)

 

80 mg

 

81 (82.7%)

 

3 (1.5%)

 

 100 mg

 

11 (11.2%)

 

0 (0.0%)

 

Day 3 Anti Xa activity (IU/mL)

69

0.58 (0.48, 0.66)

 

n/a

n/a

Day 5 Anti Xa activity (IU/mL)

63

0.58 (0.47, 0.65)

 

n/a

n/a

Heparin new dosage [mg]

30

  

n/a

n/a

 40 mg

 

3 (10.0%)

   

 60 mg

 

19 (63.3%)

   

 80 mg

 

4 (13.3%)

   

 100 mg

 

4 (13.3%)