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Table 3 Laboratory tests and vital parameters

From: Intermediate dose enoxaparin in hospitalized patients with moderate-severe COVID-19: a pilot phase II single-arm study, INHIXACOVID19

 

Interventional cohort

Observational cohort

P-value

N

Median (IQR) or n (%)

N

Median (IQR) or n (%)

WBC [10^9/mm3]

98

6.26 (4.20, 8.51)

202

6.42 (4.50, 8.55)

0.73

RBC [10^12/mm3]a

98

4.69 (4.58, 4.79)

202

4.58 (4.49, 4.67)

0.17

Hb [g/dL]

98

13.7 (12.7, 14.7)

202

13.5 (12.2, 14.6)

0.26

Neutrophils [10^9/mm3]

96

4.53 (2.89, 6.83)

187

4.56 (3.19, 7.11)

0.48

Lymphocytes [10^9/mm3]

96

1.10 (0.79, 1.56)

187

0.98 (0.74, 1.47)

0.16

Eosinophils [10^9/mm3]

96

0 (0,0)

187

0 (0, 0)

0.40

Platelets [10^9/mm3]

97

224 (170, 275)

201

206 (160, 255)

0.08

CRP [mg/dL]

94

8.15 (2.32, 14.50)

196

7.27 (2.66, 12.30)

0.33

PCT [ng/mL]

73

0.1 (0.1, 0.2)

97

0.1 (0.1, 0.2)

0.86

aPTT [ratio]

90

1.02 (0.90, 1.34)

140

1.09 (0.99, 3.64)

0.06

INR

90

1.07 (1.02, 1.12)

181

1.08 (1.02, 1.12)

0.62

D-dimer [ng/mL]

x ULN (upper limit of the reference range) mean, (min, max)

80

682 (355, 963)

1.16

2.3 (0.21, 36)

123

618 (417, 1013)

1.32

1.80 (0.32, 12.7)

0.28

Glucose [mg/dL]

94

112 (94, 145)

184

115 (96, 137)

0.95

Urea [mg/dL]

87

35 (27, 46)

136

36 (28, 48)

0.63

Creatinine [mg/dL]

98

0.87 (0.71, 1.02)

200

0.87 (0.72, 1.10)

0.30

AST [IU/L]

95

35 (26, 53)

159

33 (23, 47)

0.14

ALT [IU/L]

97

33 (20, 52)

199

26 (18, 38)

0.06

Bilirubin [mg/dL]

94

0.51 (0.40, 0.76)

142

0.60 (0.42, 0.88)

0.21

LDH [IU/L]

92

281 (233, 358)

169

284 (234, 382)

0.76

Triglycerides [mg/dL]a

59

109 (99, 119)

24

128 (109, 148)

0.05

Ferritin [mcg/L]

86

499 (259, 900)

89

448 (217, 753)

0.29

Fibrinogen [mg/dL]

79

546 (471, 633)

80

544 (437, 650)

0.72

CPK [IU/L]

82

97 (58, 189)

99

92 (47, 211)

0.50

Troponin [ng/L]

65

6.0 (5.0, 11.0)

43

8.0 (6.0, 13.0)

0.12

IL-6 [pg/mL]

80

20.0 (7.9, 40.7)

83

25.0 (10.6, 46.6)

0.67

Systolic blood pressure

98

125 (115, 135)

201

125 (120, 140)

0.74

Diastolic Blood Pressure

98

80 (70, 80)

199

75 (70, 80)

0.53

MAP

98

93.3 (84.3, 99.3)

199

93.3 (83.3, 100.0)

0.82

Pulse ratea

97

85 (82, 87)

200

83 (82, 85)

0.50

Respiratory Rate

84

20 (18, 24)

145

20 (18, 24)

0.22

  1. aMean and 95% CI are reported and p-value was obtained from t-test for independent samples