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Table 3 Associations between HCW self-reported symptoms and SARS-CoV-2 seropositivity of HCW study population and subgroups segregated by prior rt-PCR testing

From: Risk factors for SARS-CoV-2 seropositivity in a health care worker population during the early pandemic

 

All HCWs (n = 1,557)

Not tested by rt-PCR (n = 1,138)

Tested by rt-PCR (n = 419)

 

HCWs,

n (%)

COVID-19 AB prevalence,

n (%)

Adjusted OR

(95% CI)1

HCWs,

n (%)

COVID-19 AB prevalence,

n (%)

Adjusted OR

(95% CI)1

HCWs,

n (%)

COVID-19 AB prevalence,

n (%)

Adjusted OR

(95% CI)1

Total

1557 (100)

165 (10.6)

 

1138 (100)

91 (8.0)

 

419 (100)

74 (17.7)

 

Symptoms 2

         

Sore throat

633 (40.7)

79 (12.5)

1.38 (1.00-1.92)

405 (35.6)

41 (10.1)

1.47 (0.95–2.27)

228 (54.4)

38 (16.7)

0.95 (0.56–1.60)

Fatigue

429 (27.6)

63 (14.7)

1.77 (1.25–2.49)

244 (21.4)

17 (7.0)

0.79 (0.44–1.35)

185 (44.2)

46 (24.9)

2.94 (1.72–5.12)

Muscle aches

361 (23.2)

55 (15.2)

1.76 (1.23–2.50)

198 (17.4)

15 (7.6)

0.89 (0.48–1.56)

163 (38.9)

40 (24.5)

2.20 (1.30–3.74)

New cough

470 (30.2)

54 (11.5)

1.11 (0.78–1.57)

292 (25.7)

18 (6.2)

0.65 (0.36–1.09)

178 (42.5)

36 (20.2)

1.50 (0.89–2.53)

New chills

327 (21.0)

51 (15.6)

1.79 (1.24–2.55)

183 (16.1)

12 (6.6)

0.74 (0.37–1.34)

144 (34.4)

39 (27.1)

2.61 (1.55–4.44)

Fever

318 (20.4)

48 (15.1)

1.67 (1.15–2.39)

177 (15.6)

11 (6.2)

0.67 (0.33–1.24)

141 (33.7)

37 (26.2)

2.38 (1.40–4.04)

Anosmia

95 (6.1)

33 (34.7)

5.34 (3.33–8.45)

40 (3.5)

5 (12.5)

1.67 (0.56–4.08)

55 (13.1)

28 (50.9)

7.67 (4.05–14.76)

Dyspnea

200 (12.8)

27 (13.5)

1.38 (0.87–2.13)

113 (9.9)

8 (7.1)

0.83 (0.36–1.68)

87 (20.8)

19 (21.8)

1.61 (0.86–2.91)

  1. 1 Adjusted ORs and 95% CI are adjusted for age, gender, race/ethnicity, known COVID-19 exposure at home, role, location, and whether individual cared for COVID-19 patient
  2. 2 HCWs may report multiple exposures and/or symptoms. Each adjusted OR corresponds to relative odds of being COVID-19 AB seropositive for individuals who reported versus did not report the specified exposure or symptom
  3. Ab: antibody, HCW: health care worker, CI: confidence interval, rt-PCR: reverse transcriptase polymerase chain reaction