Table 2 Clinical parameters, malaria severity criteria, and therapeutic management of patients

Length of hospital stay [median, IQR]

Overall case fatality rate (%)

4 [3–6]

1 (0.9)

Clinical characteristics

 Median hemoglobin at admission [IQR]

 Median parasitemia, % [IQR]

12.5 [10.8–14.3]

5.6 [1.5–10]

Severe malaria description

Number of severe malaria criteria [median, IQR]

 1 (%)

 2 (%)

 3 (%)

 4 (%)

 5 (%)

 > 5 (%)

 Missing data (%)

Identified severity criteria (%)

 Hyperparasitemia (> 4%)

 Jaundice

 Hyperlactatemia

 Impaired consciousness/coma

 Acute renal failure (creat > 265 µmol/L)

 Macroscopic hemoglobinuria

 Respiratory failure

 Circulatory collapse/shock

 Acidosis

 Anaemia < 7 g/dL

 Multiple convulsions

 Bleeding

 Hypoglycemia (< 2.2 mmol/L)

2 [1–3]

45 (41)

25 (22,7)

20 (18.2)

11 (10)

3 (2.7)

3 (2.7)

3 (2.7)

59 (53.6)

43 (39.1)

28 (25.5)

24 (21.8)

18 (16.4)

16 (14.5)

12 (10.9)

12 (10.9)

10 (9.1)

7 (6.4)

2 (1.8)

2 (1.8)

0 (0)

Treatment management

Artesunate use

 First line (%)

 Second line (%)

 Missing data (%)

Median number of AS doses [IQR]

87 (79.1)

22 (20)

1 (0.9)

3 [3.4]

Switch to oral therapy

 Piperaquine/artenimol (%)

 Artemether/lumefantrine (%)

 Atovaquone/proguanil (%)

 Chloroquine (%)

 None (%)

 Unknown (%)

47 (42.7)

32 (29.1)

23 (21)

1 (0.9)

2 (1.8)

5 (4.5)

Negative parasitemia 72 h after AS initiation

 Yes (%)

 No (%)

 Missing data (%)

 Death (%)

79 (71.8)

17 (15.5)

13 (11.8)

1 (0.9)