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Table 2 Outcomes

From: Clinical utility of methicillin-resistant Staphylococcus aureus nasal PCR to streamline antimicrobial use in treatment of diabetic foot infection with or without osteomyelitis

 

PRE (n = 83)

POST (n = 68)

P-value

Primary Outcome

Duration of empiric MRSA-targeted antibiotic therapy (hours, median [IQR])

72 [27–120]

24 [12–72]

< 0.01

Secondary Outcomes

MRSA coverage added back for MRSA (%)

0.0

0.0

---

AKI (%)

15.7

6.1

0.07

LOS (days, median [IQR])

8.0 (5.0–13.0)

9.0 (6.3–14.0)

0.32

In-hospital mortality (%)

2.4

2.9

1.00

9-month readmission due to DFI (%)

18.1

31.3

0.06

  1. Abbreviations: methicillin-resistant Staphylococcus aureus (MRSA), acute kidney injury (AKI), length of stay (LOS), interquartile range (IQR), pre-protocol implementation (PRE), post-protocol implementation (POST)