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Table 4 Protective factor and predictors of PC and 30-day mortality in other studies from 2012–2021

From: Epidemiology, antifungal susceptibility, risk factors, and mortality of persistent candidemia in adult patients in China: a 6-year multicenter retrospective study

Authors

Country or region

study period

study design

samples

No of samples

Protective factor for PC

Independent risk factors for PC

Predictors of 30-day mortality

Reference

Ala-Houhala et al.

Finland

2007–2016

Retrospective, cohort

single-center (two hospital district )study

Adult (75 persistent

and 151 non-persistent candidemia patients)

226

early source control

CVC, metastatic infection foci, ineffective empirical treatment

-

4

Agnelli .et al

Spain

2010–2018

Retrospective, observational,

single-center study

Adult (35 persistent

and 220 non-persistent candidemia patients)

255

-

undetected site of infection

-

15

Kang et al.

South Korea

2007–2014

Retrospective, study

(2 tertiary general hospitals)

Adult (72 persistent

and 117 non-persistent candidemia patients)

189

 

CVC, longer hospital stay, severe sepsis

C. tropicalis, Septic shock, Corticosteroid within the past 30 days

9

Fu et al.

China

2012–2015

Retrospective, observational,

single-center study

Neonates (28 persistent

and 20 non-persistent candidemia patients)

48

 

Intubation and Mechanical ventilation

 

16

Hammoud et al.

Kuwait

2007–2010

Retrospective, observational,

single-center study

Neonates (54 persistent

and 34 non-persistent candidemia patients)

88

 

female gender, presence of CVC and platelet count

< 50*109/L

 

5

Robinson et al.

USA

2000–2010

Retrospective, observational,

single-center study hospitals)

Neonates (9 persistent

and 26 non-persistent candidemia patients)

37

 

antifungal therapy

was started > 1 day from positive blood culture

 

21

This study

China

2016–2021

Retrospective, observational, multicentre, cohort study

Adult (36 persistent

and 182 non-persistent candidemia patients)

218

male

the use of broad-spectrum antibiotics and fluconazole

Candida tropicalis bloodstream infection

This study

  1. CVC: central venous catheter