Authors | Country or region | study period | study design | samples | No of samples | Protective factor for PC | Independent risk factors for PC | Predictors of 30-day mortality | Reference |
---|---|---|---|---|---|---|---|---|---|
Ala-Houhala et al. | Finland | 2007–2016 | Retrospective, cohort single-center (two hospital district )study | Adult (75 persistent and 151 non-persistent candidemia patients) | 226 | early source control | CVC, metastatic infection foci, ineffective empirical treatment | - | 4 |
Agnelli .et al | Spain | 2010–2018 | Retrospective, observational, single-center study | Adult (35 persistent and 220 non-persistent candidemia patients) | 255 | - | undetected site of infection | - | 15 |
Kang et al. | South Korea | 2007–2014 | Retrospective, study (2 tertiary general hospitals) | Adult (72 persistent and 117 non-persistent candidemia patients) | 189 |  | CVC, longer hospital stay, severe sepsis | C. tropicalis, Septic shock, Corticosteroid within the past 30 days | 9 |
Fu et al. | China | 2012–2015 | Retrospective, observational, single-center study | Neonates (28 persistent and 20 non-persistent candidemia patients) | 48 |  | Intubation and Mechanical ventilation |  | 16 |
Hammoud et al. | Kuwait | 2007–2010 | Retrospective, observational, single-center study | Neonates (54 persistent and 34 non-persistent candidemia patients) | 88 |  | female gender, presence of CVC and platelet count < 50*109/L |  | 5 |
Robinson et al. | USA | 2000–2010 | Retrospective, observational, single-center study hospitals) | Neonates (9 persistent and 26 non-persistent candidemia patients) | 37 |  | antifungal therapy was started > 1 day from positive blood culture |  | 21 |
This study | China | 2016–2021 | Retrospective, observational, multicentre, cohort study | Adult (36 persistent and 182 non-persistent candidemia patients) | 218 | male | the use of broad-spectrum antibiotics and fluconazole | Candida tropicalis bloodstream infection | This study |