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Table 1 Negative conversion of viral RNA among 603 cases with Univariate analysis

From: Factors associated with negative conversion of viral RNA in hospitalized children infected with SARS-CoV-2 Omicron variant in Shanghai, China: a retrospective analysis

Factors

Count (%)

Negative conversion rate (%)

\(\mathbf X^2\)1 

P

7 days

14 days

21 days

Sex

 Male

336(55.7)

9.5

76.8

97.3

2.335

0.126

 Female

267(44.3)

9.0

76.4

98.3

Age

  < 3

373(61.9)

3.5

73.2

98.7

32.054

0.000*

 -5

107(17.7)

14.0

83.2

97.2

  

 6–11

96(15.9)

25

86.5

99.0

  

 12–17

27(4.8)

30.0

85.2

88.9

BMI

 Underweight

91 (15.1)

18.7

73.6

95.6

2.485

0.478

 Normalweight

277 (45.9)

9.4

77.6

97.8

 Overweight

121 (20.1)

9.9

78.5

99.2

 Obesity

114 (18.9)

10.7

79.8

99.1

Underlying conditions2

 No

454(75.3)

11.5

79.7

98.5

2.530

0.112

 Yes

149(24.7)

10.7

71.1

95.6

Allergic history

 No

495(82.1)

11.1

77.4

98.0

0.000

0.990

 Yes

108(17.9)

12.0

78.7

97.2

The severity of clinical outcome

 Asymptomatic

24(4.0)

54.2

95.8

100

30.425

0.000*

 Mild

399(66.2)

9.8

78.4

98.7

 Moderate

179(29.7)

8.9

73.7

96.6

 Severe

1(0.2)

0

0

0

Fever

 No

77(12.8)

37.8

84.4

98.7

14.963

0.000*

 Yes

526(87.2)

7.4

76.6

97.9

Cough

 No

282(46.8)

13.8

75.9

97.5

1.199

0.549

 Non-productive cough

215(35.7)

6.5

81.4

99.1

 Productive cough

106(17.6)

14.2

74.5

97.2

Sore throat

 No

554(91.9)

10.8

76.4

98.0

.215

0.022*

 Yes

49(8.1)

16.3

91.8

98.0

Rhinobyon

 No

549(91.0)

11.5

78.0

98.0

0.301

0.583

 Yes

54(9.0)

9.3

74.1

98.1

Running nose

 No

533(88.4)

11.8

77.9

97.9

0.648

0.421

 Yes

70(11.6)

7.1

75.7

98.6

Appetite

 Normal

510 (84.6)

12.9

66.0

98.0

3.306

0.069

 Abnormal

93 (15.4)

2.2

75.3

97.8

Defecation

 Normal

440(73.0)

13.0

81.6

98.6

13.271

0.000*

 Abnormal

163(27.0)

6.7

66.9

96.3

Personal vaccination

 Unvaccinated

522(88.6)

7.7

75.1

97.9

71.862

0.000*

 1dose

12(1.5)

33.3

75

100

 2doses

69(9.9)

34.8

95.7

98.6

Household vaccination rates

  ≤ 0.25

58(9.6)

5.2

56.9

98.3

36.019

0.000*

 0.26–0.50

230(38.1)

5.7

75.2

99.1

 0.51–0.75

219(36.3)

13.7

80.8

95.9

 0.76–1

96(15.9)

22.9

88.5

100

Therapy method

 Medical observation

145(24.0)

13.1

76.6

98.0

0.173

0.678

 Symptomatic treatment

458(76.0)

10.7

77.9

98.0

Ct-values of N

  < 20

74(18.4)

0

75.7

97.3

4.083

0.130

 20–30

305(50.6)

5.9

77.7

98.4

  > 30

224(37.1)

22.3

57.4

97.8

Ct-values of ORFab

  < 20

68(11.3)

0

77.9

97.1

4.609

0.100

 20–30

292(48.4)

5.8

76.4

98.3

  > 30

243(40.3)

21.0

79.0

97.9

  1. *the difference was statistically significant
  2. 1\(\mathrm X^2\) value and P values were calculated by Log rank test
  3. 2Underlying conditions included Asthma, Eczema, Rhinitis, conjunctivitis, tic disorders, ADHD, diabetes, lung disease, kidney disease, cancer, and congenital disease