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Table 2 Successful and unsuccessful Xpert HPV tests for HPV detection using oral samples in a sample of people living with HIV (HIV) in Pune, India

From: Challenges with the use of Xpert HPV as a screening tool for oral HPV among people living with HIV (PLHIV): experiences from Pune, India

 

Total

n (%)

Unsuccessful

Successful

p-value

Samples reported as invalid

n (%)

Samples reported as error

n (%)

Samples reported either as positive or negative for HPV

n (%)

 

Total N

426

100 (23.5)

27 (6.3)

299 (70.2)

-

Procedure of collection and processing a

Procedure 1

Procedure 2

335 (78.6)

91 (21.4)

78 (78.0)

22 (22.0)

21 (77.8)

6 (22.2)

236 (78.9)

63 (21.1)

0.9

Sex

Female

Male

208 (48.8)

218 (51.2)

48 (48.0)

52 (52.0)

14 (51.8)

13 (48.2)

146 (48.8)

153 (51.2)

0.9

Age

Median age in years (IQR)

40 (34–46)

40 (33–45)

42 (37–45)

40 (34–46)

0.3

Betel quid or smokeless tobacco use b

Never

Ever

257 (60.3)

169 (39.7)

55 (55.0

45 (45.0)

16 (59.3)

11 (40.7)

186 (62.2)

113 (37.8)

0.4

Smoking history

Never

Ever

353 (82.9)

73 (17.1)

86 (86.0)

14 (14.0)

25 (92.6)

2 (7.4)

242 (80.9)

57 (19.06)

0.2

Alcohol use

Never

Ever

279 (65.5)

147 (34.5)

57 (57.0)

43 (43.0)

20 (74.1)

7 (25.9)

202 (67.6)

97 (32.4)

0.1

Lifetime multiple sexual partners c

No

Yes

312 (73.2)

114 (26.8)

73 (73.0)

27 (27.0)

22 (81.5)

5 (18.5)

217 (72.6)

82 (27.4)

0.6

Oral sex d

No

Yes

374 (87.8)

52 (12.2)

92 (92.0)

8 (8.0)

25 (92.5)

2 (7.4)

257 (85.9)

42 (14.1)

0.2

Self identify as MSM e

No

Yes

415 (97.4)

11 (2.6)

100 (100.0)

0 (0.0)

26 (96.3)

1 (3.7)

290 (97.0)

9 (3.0)

0.1

Suspected OPMD f

No

Yes

345 (81.0)

81 (19.0)

78 (78.0)

22 (22.0)

23 (85.2)

4 (14.8)

244(81.6)

55 (18.4)

0.7

Time updated CD4 counts (cells/mm 3 )

< 500

>= 500

Missing

199 (46.7)

221(51.9)

6 (1.4)

47 (47.0)

50 (50.0)

3 (3.0)

13 (48.2)

14 (51.8)

0 (0.0)

139 (46.5)

157 (52.5)

3 (1.0)

0.7

  1. IQR: Interquartile range (25th quartile to 75th quartile)
  2. aProcedure 1: oral sample collected using oral rinse only. Testing suspension prepared after double centrifugation of oral rinse; Procedure 2: oral sample collected using cytobrush scraping of buccal mucosa + oral rinse. Testing suspension prepared by pooling suspension prepared from oral rinse after double centrifugation + cytobrush fluid
  3. bBetel quid: Locally available form is called paan (areca nut + slaked lime + condiments, wrapped in a betel leaf used with or without the addition of chewing tobacco); Smokeless tobacco use: use of tobacco forms that are not burned. Locally available forms are khaini (tobacco + slaked lime); gutka (tobacco + areca nut + slaked lime); mishri (roasted powdered tobacco); snuff; paan masala
  4. cMultiple sexual partners: ≥1 lifetime sexual partner
  5. dOral sex: given oral sex in their lifetime
  6. eMSM: Men who have sex with men
  7. fOPMD: Oral potentially malignant disorders