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Table 3 Treatment and clinical outcomes of patients by age groups

From: Evaluation of methicillin-resistant Staphylococcus aureus (MRSA) bacteremia: Epidemiology, clinical characteristics, and outcomes in the older patients in a tertiary teaching hospital in Malaysia

 

18–64 years

(n = 136)

≥ 65 years

(n = 139)

p-value

Empirical antibiotics, n (%)

133 (97.8)

137 (98.6)

0.760

Effective MRSA empiric therapy, n (%)

19 (14.2)

25 (18.3)

0.374

Targeted MRSA treatment, n (%)

108 (80.6)

102 (73.4)

0.515

Vancomycin

103 (75.7)

99 (71.2)

0.397

Linezolid

2 (1.5)

1 (0.7)

0.549

Vancomycin + Linezolid

3 (2.2)

2 (1.4)

0.303

None

28 (20.6)

37 (26.6)

0.239

Treatment duration, mean (SD)a days

16.27 (18.1)

11.65 (13.4)

0.017*

Appropriate treatment duration, n (%)

102 (94.4)

46 (43.4)

0.005*

Infectious disease team consult, n (%)

45 (41.3)

32 (30.5)

0.100

Repeated blood cultures obtained, n (%)

92 (67.6)

73 (52.5)

0.010*

Persistent bacteremia, n (%)

37 (27.2)

35 (25.2)

0.281

Recurrent bacteremia, n (%)

12 (8.9)

8 (5.8)

0.422

Overall all-cause mortality, n (%)

86 (63.2)

115 (82.7)

< 0.001*

In hospital mortality, n (%)

39 (28.7)

78 (56.1)

< 0.001*

Early mortality (14 days), n (%)

21 (15.4)

44 (31.7)

0.002*

Mortality in 30 days, n (%)

32 (23.5)

67 (48.2)

< 0.001*

Mortality in 180 days, n (%)

61 (44.9)

100 (71.9)

< 0.001*

  1. *p-value < 0.05 indicates statistical significance
  2. aSD: Standard deviation