Fig. 3

Projected levels of antibiotic resistance from 2000 to 2018 (for ciprofloxacin, cefixime and azithromycin) or 2030 (for ceftriaxone). Panel A, single-step model, panel B, multi-step model in heterosexual men and women (HMW) and men who have sex with men (MSM). The lines correspond to median projections and the shaded areas to 95% prediction intervals. The 5% threshold is shown by the dotted line. Circles show the proportion of resistant isolates in the GRASP data. Triangles indicate the period during which each antibiotic has been recommended or is predicted to be recommended (ceftriaxone) as a first-line empirical treatment