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Table 2 Post-COVID neuropsychological manifestations 12 weeks after the primary COVID-19

From: Effect of fluvoxamine on preventing neuropsychiatric symptoms of post COVID syndrome in mild to moderate patients, a randomized placebo-controlled double-blind clinical trial

Symptom

Fluvoxamine (n = 42)

Placebo (n = 43)

P-value*

Relative Risk

Primary outcome

 Fatigue

9 (21.4%)

19 (44.2%)

0.026

0.48 (0.25–0.95)

Secondary outcome

 Headache

3 (7.1%)

6 (14%)

0.483

0.51 (0.14–1.91)

 Memory impairment

2 (4.8%)

5 (11.6%)

0.433

0.41 (0.08–1.99)

 Poor concentration

8 (19%)

7 (16.3%)

0.738

1.17 (0.46–2.93)

 Insomnia

9 (21.4%)

10 (23.3%)

0.840

0.92 (0.41–2.03)

 Aggression

1 (2.4%)

4 (9.3%)

0.360

0.25 (0.03–2.19)

 Anxiety

8 (19%)

13 (30.2%)

0.232

0.63 (0.29–1.36)

 Depression

1 (2.4%)

7 (16.3%)

0.058

0.14 (0.02–1.13)

 Distorted Taste

3 (7.1%)

8 (18.6%)

0.115

0.38 (0.11–1.34)

 Distorted Smell

6 (14.3%)

11 (25.6%)

0.193

0.56 (0.22–1.37)

 Myalgia

5 (11.9%)

7 (16.3%)

0.563

0.73 (0.25–2.12)

 PCS

32 (76.2%)

35 (81.4%)

0.557

0.93 (0.75–1.16)

  1. PCS Post-COVID syndrome
  2. * Statistically significant p-values are bolded