Skip to main content
Fig. 2 | BMC Infectious Diseases

Fig. 2

From: 60-year-old male with rapidly progressive pneumocephalus caused by Clostridium septicum in the setting of an occult colonic adenocarcinoma

Fig. 2

(A) Cross section of brain demonstrating architectural disruption with necrosis and intraparenchymal hemorrhage (red arrow) as well as multiple cystic spaces within the cerebellar parenchyma (white arrows). (B) Multiple cystic spaces within brain parenchyma (20x). (C) Hypoxic-ischemic injury with diffuse hyper-eosinophilic necrotic neurons (400x). (D) Gram stain of brain tissue demonstrate gram positive rods with terminal and subterminal spores consistent with C. septicum (1000x; inset shows digital zoom of a single organism). (E) Moderately differentiated adenocarcinoma of the cecum with areas of acute inflammation and necrosis (20x). (F) Gram stain of necrotic colonic adenocarcinoma demonstrating gram positive rods consistent with C. septicum (1000x)

Back to article page

BMC Infectious Diseases

ISSN: 1471-2334

Contact us