Table 4 Multivariable Logistic Regression Analysis of Responsiveness to Influenza Vaccine
From: Factors affecting the immunogenicity of influenza vaccines in human
Variable | Category | A/H1N1 | A/H3N2 | B/Victoria | B/Yamagata | Response Status | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
OR(95%CI) | P | OR(95%CI) | P | OR(95%CI) | P | OR(95%CI) | P | OR(95%CI) | P | ||
Age Group | ≤ 5 | 1.00 | - | 1.00 | - | 1.00 | - | 1.00 | - | 1.00 | - |
|  | 6–17 | 2.83(0.98–8.12) | 0.05 | 1.51(0.38–6.08) | 0.56 | 2.30(0.87–6.11) | 0.09 | 1.91(0.36–10.12) | 0.45 | 4.31(0.43–43.07) | 0.21 |
|  | 18–64 | 2.77(1.68–4.57) | < 0.001 | 0.80(0.42–1.54) | 0.51 | 2.45(1.51-4.0) | < 0.001 | 2.45(0.58–10.28) | 0.22 | 2.64(1.08–6.46) | 0.03 |
|  | ≥ 65 | 1.32(0.76–2.28) | 0.32 | 0.38(0.18–0.81) | 0.01 | 1.46(0.86–2.47) | 0.16 | 0.36(0.07–1.89) | 0.23 | 1.16(0.42–3.25) | 0.78 |
Frequency of Colds | ≤ 1 | 1.00 | - | 1.00 | - | 1.00 | - | 1.00 | - | 1.00 | - |
|  | 2–3 | 1.17(0.56–2.46) | 0.68 | 4.00(0.75–21.58) | 0.11 | 1.28(0.63–2.60) | 0.50 | 1.39(0.45–4.33) | 0.57 | 1.38(0.33–5.69) | 0.66 |
|  | 4–6 | 0.74(0.31–1.78) | 0.50 | 10.71(1.68–68.05) | 0.01 | 0.70(0.30–1.63) | 0.41 | 0.30(0.04–2.14) | 0.23 | 0.50(0.10–2.50) | 0.40 |
|  | >6 | 2.15(0.63–7.36) | 0.22 | 7.11(0.75–67.68) | 0.09 | 1.16(0.38–3.54) | 0.79 | 1.06(0.11–9.89) | 0.96 | 0.80(0.08–8.08) | 0.85 |
Vaccination History | No | 1.00 | - | 1.00 | - | 1.00 | - | 1.00 | - | 1.00 | - |
|  | Yes | 0.40(0.26,0.62) | < 0.001 | 0.73(0.38–1.41) | 0.35 | 0.44(0.29–0.67) | < 0.001 | 0.87(0.30–2.52) | 0.79 | 0.25(0.11–0.56) | < 0.001 |
Chronic Diseases | No | 1.00 | - | 1.00 | - | 1.00 | - | 1.00 | - | 1.00 | - |
|  | Yes | 0.83(0.51–1.34) | 0.44 | 0.77(0.92 − 0.51) | 0.77 | 0.48(0.30–0.78) | 0.003 | 0.18(0.04–0.76) | 0.02 | 0.66(0.28–1.57) | 0.66 |