Table 2 Characteristics of non-reinfection and confirmed reinfection cases in Singapore
Not reinfection (n = 42) | 95% CI | Confirmed reinfection (n = 32) | 95% CI | p-value | |
|---|---|---|---|---|---|
Male (%) | 39 (93) | 32 (100) | |||
Average age, years (range) | 34 (22–51) | 35 (26–47) | |||
Interval between 1st and 2nd episode, days (range) | 186 (1-410) | 144–228 | 297 (1-397) | 267–327 | < 0.001 |
Ct value of initial PCR at 2nd episode, mean (range) | 34 (19–42) | 32–36 | 23 (9–38) | 20–26 | < 0.001 |
Repeat PCR performed during 2nd episode (%) | 18 | 17 (53.1) | |||
Mean interval to repeat PCR, days (range) | 2.6 (1–7) | 1.9 (1–10) | |||
Negative results on repeat PCR (%) | 10 (56) | 2 (12) | |||
Mean Ct value of positive result on repeat PCR (range) | 33 (17–40) | 27–40 | 22 (16–32) | 18–25 | < 0.001 |
Vaccinated (%) | 1 (2) | 0 (0) | |||
Symptoms at 2nd episode | |||||
Fever (%) | 4 (9) | 2 (6) | 0.09 | ||
Acute respiratory symptoms (%) | 8 (19) | 7 (22) | 0.1 | ||
Asymptomatic (%) | 26 (62) | 24 (75) | 0.1 | ||
Whole genome sequencing performed (%) | 5 (12) | 26 (81) | |||
Initial quantitative serology performed at 2nd episode (%) | 11 (26) | 14 (44) | |||
Mean cPASS inhibition, % (range) | 67 (21–100) | 49–85 | 72 (14–100) | 50–95 | 0.7 |
Mean Roche S titre, unit (range) | 969 (7-8560) | 737.2-2674.5 | 3770 (18-11460) | 1131.7-6407.4 | 0.08 |
Mean Roche N titre, unit (range) | 66 (9-200) | 25–106 | 81 (0.7–265) | 25.1-137.4 | 0.7 |
Consolidation on CXR at 2nd episode (%) | 1 (2) | 0 (0) | |||
Intensive care unit admission at 2nd episode (%) | 0 (0) | 0 (0) | |||
Oxygen supplementation required at 2nd episode (%) | 0 (0) | 0 (0) |