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Table 3 Univariate Cox regression analysis of demographic factors and laboratory results

From: A clinical indicator-based prognostic model predicting treatment outcomes of pulmonary tuberculosis: a prospective cohort study

Variables

HR (95% CI)

P

Sex

  

  Males

1

 

  Females

0.983 (0.419, 2.307)

0.969

Age

  

  ≤60 years

1

 

  > 60 years

2.425 (1.185, 4.960)

0.015

BMI

  

  <18.5 kg/m2

1

 

  ≥18.5 kg/m2

1.063 (0.453, 2.495)

0.887

Tobacco smoking

  

  Never

1

 

  Ever

1.133 (0.560, 2.291)

0.729

Alcohol drinking

  

  Never

1

 

  Ever

0.930 (0.444, 1.946)

0.846

Education

  

  Illiterate or semi-illiterate

1

 

  Primary school

0.489 (0.179, 1.337)

0.164

  Middle school

0.424 (0.148, 1.212)

0.109

  High school

0.368 (0.109, 1.247)

0.108

  University or college education

0.460 (0.091, 2.316)

0.346

Marriage status

  

  Unmarried

1

 

  Married

2.692 (0.634, 11.420)

0.179

  Divorced or widowed

2.274 (0.317, 16.260)

0.413

Economic level

  

  Top

1

 

  Middle

1.868 (0.396, 8.804)

0.429

  Bottom

1.518 (0.343, 6.717)

0.582

Occupational status

  

  Farmer

1

 

  Laborer/sales/housekeeping

0.544 (0.187,1.581)

0.263

  Professional/supervisory/technical

1.754 (0.685, 4.490)

0.242

Diabetes mellitus

  

  No

1

 

  Yes

1.529 (0.648, 3.617)

0.332

ATT history

  

No

1

 

Yes

2.212 (0.911, 5.367)

0.079

Treatment regimen

  

  2HRZE/4HR

1

 

  Others

2.314 (0.846, 6.333)

0.102

Treatment compliance

  

  Good

1

 

  Poor

3.194 (1.087, 9.381)

0.035

Sputum smear at diagnosis

  

  0

1

 

  Scanty or 1+

0.618 (0.225, 1.696)

0.351

  2+

1.127 (0.364, 3.487)

0.836

  3+

0.725 (0.241, 2.183)

0.568

Pulmonary cavity

  

  Absence

1

 

  Presence

0.832 (0.393, 1.762)

0.631

CXR score

1.001 (0.989, 1.014)

0.876

Symptom score

1.231 (0.992, 1.529)

0.060

Delayed treatment

1.000 (0.997, 1.003)

0.800

Risk score

4.980 (3.030, 8.185)

< 0.001

  1. Abbreviations: HR, hazard ratio; CI, confidence interval; ATT, antituberculosis treatment; CXR, chest x-ray; 2HRZE/4HR: H, isoniazid; R, rifampin; Z, pyrazinamide; E, ethambutol