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Table 2 Baseline laboratory tests and clinical indicators

From: A clinical indicator-based prognostic model predicting treatment outcomes of pulmonary tuberculosis: a prospective cohort study

Characteristics

Training cohort

Validation group

P

Sputum smear, n (%)

  

0.350

  0

  Scanty or 1+

  2+

  3+

240 (69.4)

57 (16.5)

17 (4.9)

32 (9.2)

86 (65.1)

20 (15.2)

12 (9.1)

14 (10.6)

 

Pulmonary cavity, n (%)

  

0.001

  Absence

  Presence

208 (60.1)

138 (39.9)

58 (43.9)

74 (56.1)

 

CXR score, Median (IQR)

33.33 (40)

25 (40)

< 0.001

Symptom score, Mean ± SD

3.39 ± 1.62

2.14 ± 1.29

< 0.001

Delayed treatment (days), Median (IQR)

47 (71)

30 (83)

< 0.001

Red blood cell (×1012/L), Mean ± SD

4.68 ± 0.58

4.61 ± 0.59

0.288

White blood cell (×109), Median (IQR)

6.3 (5.3)

5.94 (2.54)

0.012

Platelet (×109/L), Mean ± SD

238.77 ± 99.46

252.27 ± 86.60

0.218

Hemoglobin (g/L), Mean ± SD

135.90 ± 18.57

130.82 ± 16.48

0.014

Packed cell volume (L/L), Mean ± SD

0.411 ± 0.054

0.371 ± 0.057

< 0.001

Red blood cell distribution width (%), Mean ± SD

13.94 ± 1.56

13.02 ± 1.47

< 0.001

Absolute value of lymphocytes (×109/L), Mean ± SD

1.44 ± 0.50

1.61 ± 0.52

0.003

Lymphocytes percentage (%), Mean ± SD

22.55 ± 9.14

28.21 ± 9.71

< 0.001

Monocyte absolute value (×109/L), Mean ± SD

0.55 ± 0.27

0.45 ± 0.17

< 0.001

Monocyte percentage (%), Mean ± SD

7.74 ± 2.61

7.51 ± 2.15

0.399

Absolute value of neutrophil (×109/L), Mean ± SD

4.91 ± 2.75

3.85 ± 1.82

< 0.001

Neutrophilic percentage (%), Mean ± SD

65.98 ± 12.31

61.00 ± 10.64

< 0.001

Absolute value of eosinophils (×109/L), Median (IQR)

0.1 (0.13)

0.14 (0.15)

0.009

Eosinophil percentage (%), Median (IQR)

1.6 (2)

2.50 (2.35)

< 0.001

Absolute value of basophils (×109/L), Median (IQR)

0 (0.01)

0.02 (0.01)

< 0.001

Basophil percentage (%), Median (IQR)

0.4 (0.3)

0.4 (0.2)

0.212

Total bilirubin (µmol/L), Median (IQR)

10.54 ± 8.43

11.05 ± 8.62

0.684

Alanine aminotransferase (U/L), Median (IQR)

24.80 (16.1)

15.00 (11.00)

< 0.001

Aspartate aminotransferase (U/L), Median (IQR)

25.88 (13.3)

17.05 (8.25)

< 0.001

Urea (mmol/L), Mean ± SD

4.67 ± 1.68

4.08 ± 1.27

< 0.001

Creatinine (µmol/L), Mean ± SD

67.78 ± 17.87

63.83 ± 12.18

0.037

Uric acid (µmol/L), Mean ± SD

415.38 ± 192.10

394.83 ± 149.85

0.292

Cystatin C (mg/L), Mean ± SD

1.06 ± 0.31

1.25 ± 0.48

< 0.001

β2-microglobulin (mg/L), Mean ± SD

2.40 ± 0.88

1.40 ± 0.41

< 0.001

  1. Abbreviations: CXR, chest x-ray; IQR, interquartile range; SD, standard deviation
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BMC Infectious Diseases

ISSN: 1471-2334

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