Table 3 Multivariate trends in percentage GN/GP-positive cultures and percentage of admissions prescribed antibiotics expressed as slope (95% CI)
Trend | Total | SARS-CoV-2 + | SARS-CoV-2- | Not tested | ||||
|---|---|---|---|---|---|---|---|---|
Slope (95% CI) | P | Slope (95% CI) | P | Slope (95% CI) | P | Slope (95% CI) | P | |
Slope in % positive GN/GP culture by wave | − 0.11 (− 0.26–0.05) | P = .269 | − 0.38 (− 0.54–0.22) | P = 0.023 | − 0.36 (− 0.81–0.03) | P = 0.048 | − 0.37 (− 0.48–0.26) | P < .001 |
Slope in % prescribed antibiotic therapy by wave | − 0.08 (− 0.21–0.06) | P = 0.335 | − 2.69 (− 3.06–2.31) | P < .001 | − 1.69 (− 1.91–1.47) | P < .001 | − 0.11 (− 0.28–0.06) | P = 0.203 |
Slope in % prescribed 3rd/4th generation cepahlosporins by wave | − 0.02 (− 0.14–0.09) | P = 0.667 | − 1.61 (− 1.98–1.25) | P < .001 | − 1.18 (− 1.36–0.99) | P < .001 | − 0.067 (− 0.183–0.048) | P = 0.252 |
Slope in % BLICs by wave | − 0.28 (− 0.35–0.21) | P < .001 | − 0.37 (− 0.61–0.12) | P = 0.004 | − 0.32 (− 0.45–0.19) | P < .001 | − 0.16 (− 0.24–0.07) | P = 0.001 |
Slope in % glycopeptides by wave | − 0.22 (− 0.28–0.15) | P < .001 | − 0.21 (− 0.40–0.02) | P = 0.047 | − 0.34 (− 0.46–0.22) | P < .001 | − 0.15 (− 0.22–0.07) | P < .001 |
Slope in % macrolides by wave | − 0.28 (− 0.40–0.16) | P < .001 | − 3.78 (− 4.14–3.41) | P < .001 | − 1.59 (− 1.76–1.43) | P < .001 | 0.08 (− 0.08–0.17) | P = 0.772 |