Table 1 HAdV infectious patient characteristics
Variable | Mild HAdV infection (n = 414) | Sever HAdV Pneumonia (n = 181) | P-value |
|---|---|---|---|
Demographic data | |||
Age, Median(IQR)[years] | 3.0 (1.0–4.0) | 1.0 (0.8–2.0) | < 0.001 |
Weight, Mean ± SD [kg] | 14.3 ± 4.0 | 11.3 ± 3.5 | < 0.001 |
Bornweight, Mean ± SD [g] | 3271 ± 506 | 3269 ± 566 | 0.966 |
Length in hospital, Mean ± SD [days] | 6.2 ± 2.8 | 12.0 ± 5.6 | < 0.001 |
Male, n (%) | 246 (59.4%) | 118 (65.2%) | 0.184 |
Eutocia, n (%) | 191 (46.5%) | 80 (44.7%) | 0.690 |
Fever, n (%) | 409 (98.8%) | 175(96.7%) | 0.079 |
Laboratory data | |||
White blood cell, Mean ± SD [× 10^9/L] | 8.5 ± 4.0 | 9.1 ± 5.3 | 0.155 |
Red blood cell, Mean ± SD [× 10^12/L] | 4.3 ± 0.4 | 4.2 ± 0.5 | 0.003 |
Hemoglobin, Mean ± SD [g/L] | 113.7 ± 10.9 | 108.5 ± 11.3 | < 0.001 |
Platelet, Mean ± SD [10^9/L] | 254.1 ± 100.0 | 270.8 ± 141.4 | 0.100 |
Lymphocyte, Median(IQR) [× 10^9/L] | 2.8 (2.0–3.8) | 2.9 (1.8–4.2) | 0.726 |
Neutrophils, Median(IQR) [× 10^9/L] | 3.3 (1.9–5.9) | 4.0 (2.6–6.4) | 0.013 |
Monocyte, Median(IQR) [× 10^9/L] | 0.7 (0.5–1.1) | 0.5 (0.3–0.9) | < 0.001 |
Albumin, Mean ± SD [g/L] | 39.6 ± 2.9 | 37.7 ± 4.3 | < 0.001 |
ALT, Median(IQR) [U/L] | 14.0 (11.0–19.0) | 20.0 (14.0–28.0) | < 0.001 |
AST, Median(IQR) [U/L] | 38.0 (32.0–49.0) | 58.0 (44.0–88.0) | < 0.001 |
CKMB, Median(IQR) [U/L] | 24.6 (19.9–31.1) | 31.0 (25.4–44.5) | < 0.001 |
LgHAdV, Mean ± SD | 5.9 ± 1.6 | 5.8 ± 1.9 | 0.378 |
CRP, Median(IQR) [mg/L] | 12.8 (4.2–28.2) | 11.6 (4.2–26.2) | 0.671 |
PCT, Median(IQR) [ng/ml] | 0.2 (0.1–0.5) | 0.4 (0.1–0.8) | < 0.001 |
Therapeutic measures | |||
Methylprednisolone used, n (%) | 60 (14.5%) | 130 (71.8%) | < 0.001 |
Gammaglobulin, n (%) | 39 (9.4%) | 125 (69.1%) | < 0.001 |
Fibrobronchoscopy, n (%) | 33 (8.0%) | 112 (61.9%) | < 0.001 |
Respiratory support, n (%) | < 0.001 | ||
Unused | 414 (100.0%) | 0 (0.0%) | |
Oxygen | 0 (0.0%) | 102 (56.4%) | |
CPAP | 0 (0.0%) | 69 (38.1%) | |
MV | 0 (0.0%) | 10 (5.5%) |