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Table 1 Characteristics of study participants at the time of Candida bloodstream infection

From: Candida bloodstream infection among children hospitalised in three public-sector hospitals in the Metro West region of Cape Town, South Africa

 

Total

N = 77a

C. albicans BSI

N = 38a

Non-C. albicans BSI

N = 39a

P value**

Median age (IQR) in months

7 (1–24)

5 (1–19)

9 (2–58)

0.2

Age category

    

 < 1 month

 1—12 months

 1—5 years

 > 5 years

14 (18)

29 (38)

21 (27)

13 (17)

8 (21)

15 (39)

11 (29)

4 (11)

6 (15)

14 (36)

10 (26)

9 (23)

0.5

Sex

    

 Male

 Female

38 (49)

39 (51)

21 (55)

17 (45)

17 (44)

22 (56)

0.3

HIV status

    

 HIV-infected

 HIV-uninfected

 Unknown

2 (3)

50 (65)

25 (32)

2 (5)

22 (58)

14 (37)

0 (0)

28 (72)

11 (28)

0.2

Weight-for-age, Z score category

    

 Normal weight

 Moderate underweight

 Severe underweight

41 (53)

6 (8)

30 (39)

19 (50)

2 (5)

17 (45)

22 (57)

4 (10)

13 (33)

0.5

Gestational age of infants (< 12 months of age) at birth

    

 Term

 Preterm

 Unknown

13/43 (30)

24/43 (56)

6/43 (14)

4/23 (17)

14/23 (61)

5/23 (22)

9/20 (45)

10/20 (50)

1/20 (5)

0.08

Recorded temperature (°C)

    

 < 35.5

 35.5–37.9

 ≥ 38.0

1/66 (2)

29/66 (44)

36/66 (54)

0/31 (0)

17/31(55)

14/31 (45)

1/35 (3)

12/35 (34)

22/35 (63)

0.1

Exposure to selected IV antibiotics in the preceding 12 monthsb

63 (82)

33 (87)

30 (77)

0.3

Corticosteroid therapy for more than a month

9 (12)

2 (5)

7 (18)

0.2

Presence of central venous or arterial catheter

57 (74)

30 (79)

27 (69)

0.3

Total parental nutrition

25 (33)

13 (34)

12 (31)

0.7

Necrotizing enterocolitis

11/43 (26)

8/23 (35)

3/20 (15)

0.1

Haematological/cancer patients on immunosuppressive treatment

13 (17)

2 (5)

11 (28)

0.01

Haemodialysis

2 (3)

2 (5)

0 (0)

0.2

Present in ICU at the time of Candida BSI

49 (64)

30 (79)

19 (49)

0.01

Abdominal surgery during the previous 3 months

21 (27)

11 (29)

10 (26)

0.7

Cardiac surgery during the previous 3 months

7 (9)

1 (3)

6 (15)

0.1

  1. Proportions reported as n/N (%)
  2. p-values for categorical variables calculated using Pearson’s Chi-square test or Fishers exact test and those for continuous variables calculated using Wilcoxon rank-sum test for independent variables
  3. C. albicans Candida albicans, non-C. albicans non-Candida albicans, BSI bloodstream infection, °C degrees Celsius, ICU intensive care unit, IV intravenous
  4. aN denominator used unless otherwise stated
  5. bCarbapenems, vancomycin, aminoglycosides, penicillin, cephalosporins, piperacillin tazobactam, fluoroquinolones and clindamycin
  6. **Comparison of C. albicans and non-C. albicans BSI
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BMC Infectious Diseases

ISSN: 1471-2334

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