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Table 4 Estimated Influenza-Associated Excess Respiratory or Cardiovascular Hospitalizations, in Absolute Number of Cases and per 100,000 People, by Age Group and Epidemic Season in Spanish Public Hospitals Between 2008/2009 and 2017/2018

From: Excess hospitalizations and mortality associated with seasonal influenza in Spain, 2008–2018

  

Influenza-Associated Excess C&R Hospitalizations per Age Group

0–4

5–18

19–49

50–64

65–74

 ≥ 75

 ≥ 65

All ages

2008/2009

N

d

a,d

189a

2,099

4,724

12,459

18,438

16,546

Ratee

d

d

0.9

26.9

125.5

326.1

243.1

36

95% CI

d

d

− 3.2 to 5

14.8–38.8

96.7–154.2

249.8–401.6

196.3–288.3

23.1–47.9

2009/2010

N

455a

2,412

6,621

3,542

817a

a,d

a,d

12,844

Ratee

18.3

38.9

30.2

44.3

21.5

d

d

27.7

95% CI

− 14.8 to 0

34–0

27.5–0

35.1–0

0.4–0

vd

d

17.7–0

2010/2011

N

1,202a

393a

5,250

6,804

5,457

10,432

15,963

30,444

Ratee

48.1

6.3

24.1

83.4

142

257.4

202.2

65.4

95% CI

11.7–86.2

0.3–12.6

20.7–27.4

73.1–93

116.4–166.3

187.9–328

156.7–245.5

53.7–77

2011/2012

N

d

a,d

332a

3,227

6,860

33,068

40,098

41,665

Ratee

d

d

1.5

38.7

176.5

793.4

497.8

89.1

95% CI

d

d

− 2 to 5.3

27.7–49.5

151.5–202.1

725.6–860.4

454.1–541.9

77.2–100.7

2012/2013

N

d

a,d

1,763

3,643

2,680

10,013

12,559

16,743

Ratee

d

d

8.3

42.8

68

235.5

153.2

35.8

95% CI

d

d

4.8–11.7

32.5–52.9

42.9–91.7

168.5–301.7

110.7–195.1

24.4–47.1

2013/2014

N

1432

188a

3,553

5,702

5,493

13,716

18,382

29,924

Ratee

60.4

2.9

17.1

66

135.2

319.6

220.1

64.2

95% CI

30.8–90.6

− 2.2–8.2

14.2–20

57–74.6

112.9–155.5

261.1–376.8

183.3–256

53.8–73.7

2014/2015

N

632a

724

1,743

4,449

6,556

35,472

40,351

49,761

Ratee

27.6

11.2

8.5

50.5

155.2

826.1

473.7

107.1

95% CI

− 2.9 to 61.8

6.3–16.5

5.5–11.7

41–60.1

133.3–177.3

766.3–881.8

435.9–511.7

96.7–116.9

2015/2016

N

887a

2,155

4,669

6,181

4,948

12,127

16,479

30,430

Ratee

39.8

32.9

23.3

68.7

114.7

280.2

190.7

65.5

95% CI

1–77.2

27.2–38.8

19.9–26.7

57.4–79.1

89.3–139.1

208.6–354.9

146.1–236.8

52.9–78

2016/2017

N

d

a,d

946

4,120

7,513

34,664

42,722

45,672

Ratee

d

vd

4.8

44.7

171.7

790.9

487.8

98.3

95% CI

d

d

1.3–8.3

34.7–54.2

147.9–194.9

727.2–855.4

449.5–528.6

86.7–109.6

2017/2018

N

d

1,172

1,683

6,704

10,540

36,490

48,824

52,861

Ratee

d

17.6

8.6

71.2

235.3

827.3

549.2

113.5

95% CI

d

11.5–24.1

5.2–12.2

60.9–82

209.8–261.3

758–897.2

505.9–593.4

101.3–126

9 years meanb

N

461

515

2,236

4,770

6,086

22,049

28,202

34,894

Ratee

19.5

7.9

10.8

54.8

147.1

517.4

335.3

75

95% CI

− 79.8 to 79

0.5–12.4

7.4–14.2

44.3–64.9

122.3–171.4

450.4–584.2

293.2–377.5

63.3–86.3

3 years meanc

N

296

1,109

2,432

5,668

7,667

27,761

36,008

42,988

Ratee

13.3

16.8

12.2

61.5

173.9

632.8

409.2

92.4

95% CI

− 88.7 to 77.2

9.6–21.6

8.8–15.7

51–71.8

149–198.4

564.6–702.5

367.2–452.9

80.3–104.5

  1. CI: Confidence interval; C&R: Respiratory or cardiovascular; N: Number of influenza-associated excess C&R hospitalizations
  2. a P-value associated to the ILI incidence variable > 0.05; b Includes the following seasons: 2008/2009, 2010/2011, 2011/2012, 2012/2013, 2013/2014, 2014/2015, 2015/2016, 2016/2017, 2017/2018. Excludes season 2009/10, since it was affected by the 2009 influenza A (H1N1) pandemic. Seasonal negative excess estimates were truncated to zero to compute the mean; c Includes the most recent seasons, namely 2015/2016, 2016/2017, 2017/2018. Seasonal negative excess estimates were truncated to zero to compute the mean; d No influenza-associated excess hospitalizations estimated for this age group/season; e Rate of influenza-associated excess C&R hospitalizations per 100,000 people