The clinical manifestation and the influence of age and comorbidities on long-term chikungunya disease and health-related quality of life: a 60-month prospective cohort study in Curaçao

Table 3 Persistent rheumatic symptoms of affected patients related to age at acute disease (n = 62)

	Age categories at acute disease (years)
	Total	18–29		30–44		45–59		> 60
	n = 62	n = 6		n = 15		n = 26		n = 15
	n (%)	n (%)	P-value^a	n (%)	P-value^a	n (%)	P-value^a	n (%)	P-value^a
Arthralgia in the^b
Back/neck	31 (50.0)	2 (33.3)	.67	8 (53.3)	1.000	11 (42.3)	.44	10 (66.7)	.24
Upper extremities^c	46 (74.2)	3 (50.0)	.17	14 (93.3)	.09	18 (69.2)	.56	11 (73.3)	1.000
Lower extremities^d	52 (83.9)	6 (100)	.58	13 (86.7)	1.000	20 (76.9)	.30	13 (86.7)	1.000
Weakness in the^b
Back/neck	15 (24.2)	2 (33.3)	.63	5 (33.3)	.52	4 (15.4)	.23	4 (26.7)	.74
Upper extremities^c	30 (48.4)	2 (33.3)	.67	9 (60.0)	.58	10 (38.5)	.21	9 (60.0)	.38
Lower extremities^d	26 (41.9)	4 (66.7)	.23	7 (46.7)	.78	7 (26.9)	.07	8 (53.3)	.37
Myalgia	36 (58.1)	3 (50.0)	.69	10 (66.7)	.55	12 (46.2)	.13	11 (73.3)	.23

^aGroups were compared using the Fisher’s exact test, with Bonferroni multiple post hoc analysis, two-sided P value corresponds to the comparison of the proportions of rheumatic symptoms and age categories among affected patients; ^bMultiple answers were possible; ^cUpper extremities refers to the shoulders, elbows, hands, wrists, and fingers; ^dLower extremities refers to the hips, knees, ankles, feet, and toes

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