First publication of endemic channels as part of a pediatric Antimicrobial Stewardship Program: when to turn on the alarms? Recommendations of a pediatric ASP program

Table 1 DOT* of ceftriaxone (2017–2020) and calculated quartiles

Month	Days of therapy (DOT) Ceftriaxone				Quartile method**			Geometric mean (GM) and confidence intervals (CI) method^
Month	2017	2018	2019	2020	Q1	Q2	Q3	Superior CI	GM	Inferior CI
January	48	30	20	18	18	20	30	3.75	3.09	2.43
February	18	19	20	16	16	19	20	3.20	2.89	2.58
March	39	19	31	18	18	19	31	3.83	3.08	2.32
April	28	21	17	31	17	21	31	3.89	3.10	2.32
May	37	16	27	16	16	16	27	3.70	2.95	2.21
June	28	14	28	8	8	14	28	4.23	2.69	1.15
July	23	15	21	14	14	15	21	3.33	2.78	2.23
August	24	27	18	13	13	18	27	3.82	2.90	1.98
September	40	19	21	9	9	19	21	3.85	2.73	1.61
October	26	15	16	3	3	15	16	4.64	2.18	0.00
November	29	19	10	10	10	10	19	3.42	2.54	1.66
December	37	25	14	18	14	18	25	3.64	2.92	2.21

*DOT × 1000 patient-days
^**Q1: percentile 25, Q2: percentile 50, Q3: percentile 75
^DOT (days of therapy) used to construct endemic channel and depicted in GM and CI methods should be in natural logarithm

ISSN: 1471-2334