Table 3 Percentage of antibiotics’ sensitivity toward different bacteria in Hospital “B” before and after the implementation of Antimicrobial Stewardship Program

ESBL E. coli

124

156

126

TMP/SMX ( Trimethoprim / Sulfamethoxazole)

–

1

22

22

26

Ciprofloxacin

0.88

–

23

24

24

Piperacillin-tazobactam

0.291

0.291

79

73

79

E. coli

126

177

149

Ampicillin

0.549

0.549

3

5

3

Amoxicillin—clavulanate

0.583

0.32

57

53

59

Cefuroxime

0.02

0.027

70

59

70

Ciprofloxacin

0.609

0.068

55

48

59

TMP/SMX

0.807

0.336

52

49

54

Piperacillin-tazobactam

0.012

0.185

100

93

87

Cefalexin

< 0.001

0.487

48

14

17

Levofloxacin

0.081

48

59

ESBL Klebsiella

59

32

32

Ciprofloxacin

0.21

1

20

47

50

TMP/SMX ( Trimethoprim / Sulfamethoxazole)

1

1

10

9

13

Piperacillin-tazobactam

1

1

69

66

69

Levofloxacin

–

1

47

50

Klebsiella spp

90

77

81

Amoxicillin -clavulanate

0.019

0.678

7

21

27

Amikacin

< 0.001

0.014

83

55

75

Gentamycin

< 0.001

1

70

0

1

Cefuroxime

< 0.001

0.868

70

34

37

Ceftazidime

0.001

0.009

70

39

59

Ceftriaxone

0.08

0.04

23

39

59

Ciprofloxacin

0.136

0.728

22

32

35

TMP/SMX

< 0.001

0.864

76

22

25

Ertapenem

0.035

0.017

70

53

74

Piperacillin-tazobactam

0.047

0.017

70

53

74

Imipenem

0.09

0.032

70

53

74

Meropenem

0.065

0.014

70

53

74

Tigecycline

0.099

0.032

30

47

26

Cefoxitin

 < 0.001

–

24

1

1

Cefalexin

 < 0.001

–

70

6

6

Colistin

0.081

0.014

30

47

26

Levofloxacin

0.125

 < 0.001

0

8

35

Pseudomonas aeruginosa

65

41

26

Gentamycin

0.002

1

89

63

69

Ceftazidime

0.453

0.219

85

90

73

Ciprofloxacin

 < 0.001

1

54

95

92

TMP/SMX

1

–

3

1

1

Piperacillin-tazobactam

 < 0.001

1

52

95

96

Imipenem

0.017

1

57

88

92

Meropenem

0.001

0.687

57

78

92

Tigecycline

 < 0.001

0.011

5

49

77

Levofloxacin

–

1

94

92

Colistin

1

1

94

93

92

Acinobacter baumanii

51

56

50

Amikacin

0.625

1

2

9

6

MRSA

7

3

19

Gentamycin

1

1

14

67

89

Ciprofloxacin

1

1

14

33

84

TMP/SMX ( Trimethoprim / Sulfamethoxazole)

1

1

57

33

79

Piperacillin-tazobactam

1

1

43

33

95

Levofloxacin

–

1

33

84

Erythromycin

1

1

14

33

26

Clindamycin

1

1

14

33

26

Strep. faecalis

15

13

Ampicillin

–

1

26

31

Amoxicillin-clavulanate

–

0.508

47

62

Amikacin

–

0.021

1

69

Gentamycin

–

0.07

1

54

Cefuroxime

–

0.021

1

77

Ceftazidime

–

0.003

1

92

Ceftriaxone

–

0.003

1

92

Ciprofloxacin

–

0.687

53

77

TMP/SMX

–

0.039

33

85

Ertapenem

–

0.008

20

85

Piperacillin-tazobactam

–

0.727

47

77

Imipenem

–

0.008

27

85

Meropenem

–

0.002

20

92

Tigecycline

–

 < 0.001

7

100

Levofloxacin

–

0.125

53

85

Staphylococcus aureus

55

36

15

Ampicillin

0.625

0.625

0

8

20

Amoxicillin-Clavulanate

0.006

0.375

100

69

53

Amikacin

0.006

0.004

100

69

0

Gentamycin

0.481

0.021

75

61

0

Cefuroxime

 < 0.001

 < 0.001

20

86

0

Ceftazidime

1

0.07

35

36

0

Ceftriaxone

1

0.016

25

36

0

Ciprofloxacin

0.581

0.289

44

61

47

TMP/SMX

0.21

0.18

40

64

33

Ertapenem

< 0.001

1

100

61

27

Piperacillin-Tazobactam

1

0.453

53

58

47

Tigecycline

–

< 0.001

100

13

Cefalexin

0.286

0.125

33

44

0

Levofloxacin

–

0.289

61

47

Erythromycin

0.824

0.219

51

47

1

Clindamycin

0.607

0.289

51

47

13