Study on the expression of TRIM7 in peripheral blood mononuclear cells of patients with sepsis and its early diagnostic value

Table 3 Areas under the curve of TRIM7 mRNA level and inflammatory parameters for determining sepsis

Parameter	Cut-off value	AUC	Sensitivity	Specifity	p value	95% CI
Parameter	Cut-off value	AUC	Sensitivity	Specifity	p value	Lower limit	Higher limit
WBC (10⁹/L)	14.105	0.541	0.647	0.543	0.560	0.401	0.680
CRP (mg/L)	74.955	0.676	0.676	0.657	0.012	0.547	0.805
PCT (µg/L)	3.680	0.772	0.794	0.743	0.000	0.658	0.887
TNF-α (ng/L)	49.512	0.647	0.706	0.600	0.036	0.516	0.778
IL-6 (ng/L)	47.250	0.729	0.853	0.571	0.001	0.608	0.850
TRIM7 (2^−△△Ct)	1.829	0.798	0.735	0.771	0.000	0.691	0.905

The ROC curve was applied for evaluating the early diagnostic value of TRIM7 expression and inflammatory parameters in PBMCs in sepsis
AUC area under curve, CI confidence interval, WBC white blood cell, CRP C-reactive protein, PCT procalcitonin, TNF-α tumor necrosis factor-α, IL-6 interleukin-6

ISSN: 1471-2334