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Table 3 WHO treatment outcomes by bedaquiline treatment and DR-TB type in MDR-TB patients in South Africa

From: Bedaquiline safety, efficacy, utilization and emergence of resistance following treatment of multidrug-resistant tuberculosis patients in South Africa: a retrospective cohort analysis

WHO outcomes, n (%)

MDR

N = 3323

Pre-XDR

N = 1246

XDR

N = 1401

 

Bedaquiline

N = 1523

No bedaquiline

N = 1800

Bedaquiline

N = 1036

No bedaquiline

N = 210

Bedaquiline

N = 1180

No bedaquiline

N = 221

Cured

778 (51.1)

753 (41.8)

515 (49.7)

49 (23.3)

641 (54.3)

48 (21.7)

Treatment completed

251 (16.5)

215 (11.9)

158 (15.3)

17 (8.1)

158 (13.4)

20 (9.0)

Died

205 (13.5)

385 (21.4)

148 (14.3)

82 (39.0)

224 (19.0)

105 (47.5)

Lost to follow-up

254 (16.7)

397 (22.1)

182 (17.6)

49 (23.3)

117 (9.9)

19 (8.6)

Treatment failed

35 (2.3)

50 (2.8)

33 (3.2)

13 (6.2)

40 (3.4)

29 (13.1)

Treatment success (cured + treatment completed)

1029 (67.6)

968 (53.8)

673 (65.0)

66 (31.4)

799 (67.7)

68 (30.8)