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Table 6 Comparison of samples submitted for routine diagnostic testing and samples tested through the surveillance study

From: Diagnostic testing practices for diarrhoeal cases in South African public hospitals

 

Routine diagnostic data (n = 1311)

Surveillance study (n = 591)

p-value

Samples per site

 Kalafong

1222 (93.2%)

311 (52.6%)

< 0.001

 Mapulaneng

68 (5.2%)

103 (17.4%)

 Matikwana

21 (1.6%)

177 (29.9%)

Age groups (years)a

 < 1

161 (13.0%)

211 (35.7%)

< 0.001

 1–4

142 (11.5%)

183 (31.0%)

 5–17

69 (5.6%)

24 (4.1%)

 18–44

540 (43.6%)

98 (16.6%)

 45+

328 (26.5%)

75 (12.7%)

Gender

 Male

581 (44.7%)

298 (50.8%)

0.016

 Female

719 (55.3%)

289 (49.2%)

Samples with pathogen detected

179/1311 (13.7%)

433 (73.3%)

< 0.001

Virus detected

34/1311 (2.6%)

289 (48.9%)

< 0.001

 Adenovirusb

10/206 (4.9%)

151 (25.6%)

< 0.001

 Rotavirusb

29/220(13.2%)

92 (15.6%)

0.394

 Norovirus

NT

84 (14.2%)

 Astrovirusb

2/40 (5.0%)

35 (5.9%)

0.814

 Sapovirus

NT

21 (3.6%)

Bacteria detected

105/1311 (8.0%)

237 (40.1%)

< 0.001

 Shigella spp.b

10/1308 (0.8%)

134 (22.7%)

< 0.001

 Campylobacterb

2/873 (0.2%)

70 (11.8%)

< 0.001

 Salmonella spp.b

17/1309 (1.3%)

21 (3.6%)

0.001

 EHECb,c

0/677 (0.0%)

9 (1.5%)

0.001

 C. difficile

76/375 (20.3%)

34 (5.8%)

< 0.001

 EPECb

0/64 (0.0%)

NT

 Vibrio spp.b

0/90 (0.0%)

NT

 Vibrio choleraeb

0/93 (0.0%)

NT

Parasites detected

47/1311 (3.6%)

96 (16.2%)

< 0.001

 Cryptosporidium spp.b

36/1210 (3.0%)

78 (13.2%)

< 0.001

 Giardia lambliab

0/1210 (0.0%)

22 (3.7%)

< 0.001

 Cystoisosopora bellib

8/1210 (0.7%)

NT

 Otherb,d

3/1210 (0.2%)

 

  1. NT not tested, EHEC enterohemorrhagic Escherichia coli, EPEC enteropathogenic Escherichia coli
  2. P-values < 0.05 indicated in bold
  3. a71 CDW cases missing ages
  4. bDenominators for CDW data refer to number tested for specific pathogen rather than total samples submitted
  5. cMolecular toxin testing done for EHEC in the surveillance study and by culture for CDW data
  6. dOther parasites include: Endolimax nana, Schistosoma mansoni, Taenia spp.