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Table 4 Self-reported adverse events according to the patients’ diaries divided into groups based on Centor Score (3 or 4) and given treatment (Penicillin V 800 mg × 4 for 5 days or Penicillin V 1 g × 3 for 10 days)

From: Clinical course of pharyngotonsillitis with group A streptococcus treated with different penicillin V strategies, divided in groups of Centor Score 3 and 4: a prospective study in primary care

 

Adverse events

CS-3 1 g × 3, 10 days

n = 104

CS-3 800 mg × 4, 5 days n = 104

CS-4 1 g × 3, 10 days

n = 105

CS-4 800 mg × 4, 5 days n = 107

No (%)

Duration (days)a

No (%)

Duration (days)a

No (%)

Duration (days)a

No (%)

Duration (days)a

Diarrhoea

29 (28)

2 (1–3)

20 (23)

1 (1–2.5)

25 (24)

2 (1–3)

22 (21)

2 (1–2.25)

Nausea or vomiting

21 (20)

2 (1–4.5)

11 (11)

1 (1–2)

11 (11)

1 (1–4)

12 (11)

2 (1.25–4.75)

Vaginal itching or discharge (women)

15 (21)

6 (4–8)

7 (10)

3 (3–5.75)

10 (16)

2 (3–10)

6 (9)

4 (1–5)

Rash

5 (5)

2(1–5)

5 (5)

3 (1–6)

6 (6)

3 (1–9)

1 (1)

3 (3–3)

  1. aMedian (interquartile range)