Fig. 2

Representative MRI findings in HIV-negative patients with CM. A 64-year-old man with HIV-negative CM. a–d DWI and ADC map showing multiple lacunar infarction in cerebellar vermis, bilateral cerebellar hemispheres and bilateral occipital lobe. e, f Gadolinium (Gd)-enhanced FLAIR showing meningeal enhancement of cerebral cortex and brain stem and cerebellum (posterior fossa exudates). g T2WI showing ventricular dilatation (hydrocephalus). h Another patient with HIV-negative CM. Gadolinium (Gd) contrast enhanced T1WI showing remarkable ring enhancement in the posterior inferior region of left splenium of corpus callosum (cryptococcoma). i–l The third patient with HIV-negative CM, DWI and ADC map showing multiple large infarctions at the left frontal, left temporal, bilateral occipital lobe