Fig. 4

The duration of viral RNA shedding and the titers of specific IgG and IgM in the three groups with SARS-CoV-2 pneumonia. A The average duration of viral RNA shedding in the FV group with SARS-CoV-2 pneumonia was significantly lower than in the UV group with SARS-CoV-2 pneumonia (adjusted P = 0.002). The average duration of viral RNA shedding in the PV group with SARS-CoV-2 pneumonia was lower than in the UV group with SARS-CoV-2 pneumonia, although the difference was not statistically significant (adjusted P = 0.835). B The median titers of SARS-CoV-2-specific IgG were significantly higher in the FV and PV groups with SARS-CoV-2 pneumonia than in the UV group with SARS-CoV-2 pneumonia (adjusted P < 0.001 and adjusted P = 0.035, respectively). C The median titers of SARS-CoV-2 specific IgM were significantly higher in the FV group with SARS-CoV-2 pneumonia than in the UV group with SARS-CoV-2 pneumonia (adjusted P = 0.007). The titers of SARS-CoV-2 specific IgM were higher in the PV group with SARS-CoV-2 pneumonia than in the UV group with SARS-CoV-2 pneumonia, although the difference was not statistically significant (adjusted P = 0.068). D Cumulative proportion of patients with detectable SARS-CoV-2 RNA by days after illness onset between the UV, PV, and FV groups with SARS-CoV-2 pneumonia. Continuous variables were analyzed by variance analysis or Kruskal‒Wallis test. Kaplan‒Meier survival analysis was used to estimate the cumulative SARS-CoV-2 RNA negativity rate. A P value of less than 0.05 (two-tailed) was considered statistically significant. FV fully vaccinated, PV partially vaccinated, UV unvaccinated, SARS-CoV-2 Severe Acute Respiratory Syndrome Coronavirus 2, IQR interquartile range