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Table 2 Multiple linear regression model of HFMD cases and RSV of selected search terms from 2016 to 2019

From: Explanation of hand, foot, and mouth disease cases in Japan using Google Trends before and during the COVID-19: infodemiology study

Search terms (English)

Search terms (Japanese)

Model summary

Standardized β

Std.Error

P-value

Virus

ウイルス

0.0507

0.019

0.007

Herpangina

ヘルパンギーナ

− 0.1034

0.033

0.002

Diarrhea

下痢

− 0.0998

0.021

< 0.001

Oral cavity (synonym)

口内

0.0290

0.015

0.049

Summer cold

夏風邪

0.1361

0.037

< .001

Adult

大人

0.1306

0.032

< .001

Young child

小児

− 0.0372

0.017

0.032

Pediatric

小児科

0.0641

0.019

0.001

Hand and foot

手足

0.8575

0.026

< 0.001

Chickenpox (colloquial term)

水疱瘡

− 0.0634

0.018

0.001

Eczema

湿疹

0.0506

0.018

0.006

Intense pain

激痛

0.0361

0.014

0.010

Exhaustion

疲れ

− 0.0474

0.021

0.024

Itch (word morphing)

痒く

0.0468

0.019

0.014

Swelling

腫れ

− 0.0481

0.022

0.033

Reduce fever

解熱

− 0.1042

0.021

< 0.001

Sole of the foot

足底

− 0.0589

0.023

0.012

Nasal mucus

鼻水

− 0.0743

0.023

0.001

  1. Adjusted R2 = 96.7%