Table 1 Pathogen characteristics and inappropriate empiric treatment
nvHABP | % | vHABP | % | VABP | % | P-value | |
|---|---|---|---|---|---|---|---|
N = 4728 (26.53%) | N = 4561 (25.60%) | N = 8530 (47.87%) | |||||
Gram stain status | |||||||
GN only | 2603 | 55.05% | 2435 | 53.39% | 4835 | 56.68% | |
IET | 278 | 10.68% | 180 | 7.39% | 449 | 9.29% | 0.001 |
Indeterminate | 200 | 7.68% | 168 | 6.90% | 329 | 6.80% | |
Non-IET | 2125 | 81.64% | 2087 | 85.71% | 4057 | 83.91% | |
GP only | 1862 | 39.38% | 1781 | 39.05% | 2987 | 35.02% | |
IET | 91 | 4.89% | 51 | 2.86% | 117 | 3.92% | 0.007 |
Indeterminate | 204 | 10.96% | 164 | 9.21% | 291 | 9.74% | |
Non-IET | 1567 | 84.16% | 1566 | 87.93% | 2579 | 86.34% | |
GN + GP | 263 | 5.56% | 345 | 7.56% | 708 | 8.30% | |
IET | 34 | 12.93% | 23 | 6.67% | 49 | 6.92% | < 0.001 |
Indeterminate | 65 | 24.71% | 46 | 13.33% | 117 | 16.53% | |
Non-IET | 164 | 62.36% | 276 | 80.00% | 542 | 76.55% | |
Specific resistant pathogens | |||||||
CR (among GN patients) | 213 | 7.43% | 186 | 6.69% | 493 | 8.89% | |
IET | 72 | 33.80% | 68 | 36.56% | 198 | 40.16% | 0.310 |
Indeterminate | 27 | 12.68% | 16 | 8.60% | 43 | 8.72% | |
Non-IET | 114 | 53.52% | 102 | 54.84% | 252 | 51.12% | |
C3R (among Enterobaterales) | 272 | 14.43% | 284 | 14.90% | 493 | 12.86% | |
IET | 66 | 24.26% | 46 | 16.20% | 86 | 17.44% | 0.032 |
Indeterminate | 16 | 5.88% | 15 | 5.28% | 42 | 8.52% | |
Non-IET | 190 | 69.85% | 223 | 78.52% | 365 | 74.04% | |