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Table 1 Clinical features

From: Association between active cytomegalovirus infection and lung fibroproliferation in adult patients with acute respiratory distress syndrome: a retrospective study

Clinical features

Total

Active CMV infection

P

N = 87

Yes (n = 14, 16.1%)

No (n = 73, 83.9%)

Age (year)

56 ± 16

62 ± 11

54 ± 17

0.103

Sex, n (%)

0.331

 Male

52 (59.8)

10 (71.4)

42 (57.5)

–

 Female

35 (40.2)

4 (28.6)

31 (42.5)

–

Weight (kg)

60.0 (50.0–67.3)

60.0 (50.0–65.0)

60.0 (52.0–67.0)

0.939

BMI (kg/m2)

22.5 (19.6–24.2)

22.5 (18.5–23.1)

22.5 (19.7–24.2)

0.538

Score of disease severity

 APACHE II

19 (15–23)

19 (14–26)

19 (15–23)

0.689

 SOFA

9 (6–11)

9 (6–13)

9 (7–11)

0.855

 qSOFA

2 (1–3)

2 (2–3)

2 (1–3)

0.834

ARDS severity, n (%)

 Mild

16 (18.4)

1 (7.1)

15 (20.5)

0.418

 Moderate

40 (46.0)

7 (50.0)

33 (45.2)

0.742

 Severe

31 (35.6)

6 (42.9)

25 (34.3)

0.755

Main causes of ARDS, n (%)

0.588

 Severe pneumonia

82 (94.3)

14 (100)

68 (93.2)

–

 Other

5 (5.7)

0 (0)

5 (6.8)

–

Vital signs

 Average blood pressure (mmHg)

80 ± 22

83 ± 24

81 ± 19

0.449

 Heart rate (bpm)

104 (86–120)

90 (83–122)

105 (87–120)

0.783

 Respiratory rate (bpm)

24 (20–31)

24 (21–30)

24 (20–32)

0.913

 Temperature (℃)

37.0 (36.6–38.0)

37.1 (36.8–38.2)

37.0 (36.6–37.9)

0.452

Comorbidities, n (%)

 Cardiovascular diseases

27 (31.0)

5 (35.7)

22 (30.1)

0.922

 Hypertension

25 (28.7)

7 (50.0)

18 (24.7)

0.110

 Diabetes

15 (17.2)

3 (21.4)

12 (16.4)

0.947

 COPD

13 (14.9)

2 (14.3)

11 (15.1)

> 0.999

 Connective tissue disease*

12 (13.8)

2 (14.3)

10 (13.7)

> 0.999

 Malignancy

12 (13.8)

2 (14.3)

10 (13.7)

> 0.999

 Cerebral thrombosis

8 (9.2)

2 (14.3)

6 (8.2)

0.830

  1. CMV: Cytomegalovirus; BMI: Body Mass Index; APACHE II: Acute Physiology and Chronic Health Evaluation II; qSOFA: Quick Sequential Organ Failure Assessment; ARDS: acute respiratory distress syndrome; CAP: community-acquired pneumonia; HAP: hospital-acquired pneumonia; COPD: chronic obstructive pulmonary disease
  2. Categorical variables were expressed as n (%), Continuous variables were expressed as Mean ± SD or Median (IQRs); *, included Systemic Lupus Erythematosus, rheumatoid arthritis, Dermatomyositis, Still’s Disease and Sjogren’s Syndrome. Bold font indicates the difference was statistically significant