Table 1 Baseline characteristics of patients hospitalized in ICU with COVID-19
From: Secondary respiratory early and late infections in mechanically ventilated patients with COVID-19
All patients | No secondary respiratory infection | With secondary respiratory infection | P value | |
|---|---|---|---|---|
N (%) | 175 | 104 (69.4) | 71 (40.6) | |
Age, years | 62 [54–70] | 62 [53–70] | 62 [55–71] | 0.897 |
Male, n (%) | 125 (71.4) | 77 (73.3) | 48 (67.6) | 0.355 |
Body Mass Index, kg/m2 | 29 [27–32] | 30 [28–33] | 27 [26–31] | 0.008 |
Any comorbidity, n (%) | 130 (74.3) | 72 (69.2) | 58 (81.7) | 0.064 |
Comorbidities, n | 1 [1, 2] | 1 [0–2] | 2 [1–3] | 0.177 |
Diabetes, n (%) | 58 (33.1) | 30 (28.8) | 28 (39.4) | 0.144 |
Arterial hypertension, n (%) | 84 (48.0) | 47 (45.2) | 37 (52.1) | 0.368 |
Cardiovascular disease, n (%) | 15 (8.6) | 7 (6.7) | 8 (11.3) | 0.292 |
COPD, n (%) | 7 (4.0) | 3 (2.9) | 4 (5.6) | 0.298 |
Asthma, n (%) | 3 (1.7) | 2 (1.9) | 1 (1.4) | 0.641 |
Smoking, n (%) | 8 (4.6) | 6 (5.8) | 2 (2.8) | 0.299 |
Obesity, n (%) | 40 (22.9) | 25 (23.8) | 15 (21.1) | 0.652 |
Cancer, n (%) | 11 (6.3) | 5 (4.8) | 6 (8.5) | 0.330 |
Chronic kidney disease, n (%) | 5 (2.8) | 4 (3.9) | 1 (1.4) | 0.342 |
Chronic liver disease, n (%) | 4 (2.3) | 2 (1.9) | 2 (2.8) | 0.698 |
Autoinmune disease, n (%) | 7 (4.0) | 4 (3.8) | 3 (4.2) | 0.900 |
HIV, n (%) | 3 (1.7) | 1 (1.0) | 2 (2.8) | 0.353 |
Immunosuppressant drugs (before admission), n (%) | 4 (2.3) | 1 (1.0) | 3 (4.2) | 0.156 |
Corticosteroids (before admission), n (%) | 8 (4.6) | 2 (1.9) | 6 (8.5) | 0.041 |
ACE inhibitors (before admission), n (%) | 18 (10.3) | 10 (9.6) | 8 (11.3) | 0.724 |
Lymphocytes at admission (cels × 103/μL) | 0.62 [0.44–0.92] | 0.61 [0.43–0.93] | 0.62 [0.45–0.94] | 0.424 |
Time from first symptoms to hospital admission, days | 7 [4–9.5] | 7 [4–10] | 7 [5–8] | 0.729 |
Transfer from another hospital, n (%) | 31 (17.7) | 19 (18.1) | 12 (16.9) | 0.793 |
APACHE II score on admission | 15 [10–22] | 15 [9–22] | 15 [10–22] | 0.818 |
SOFA score on admission | 5 [3–8] | 5 [3–8] | 5 [3–8] | 0.987 |
PaO2/FiO2 on hospital admission | 110 [78–164] | 114 [75–165] | 110 [82–158] | 0.763 |