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Table 5 Comparison of drug treatment among the four clusters

From: Clinical clustering with prognostic implications in Japanese COVID-19 patients: report from Japan COVID-19 Task Force, a nation-wide consortium to investigate COVID-19 host genetics

 

Cluster 1

Cluster 2

Cluster 3

Cluster 4

p-value

Young healthy

Middle aged

Middle aged obese

Elderly

Antibiotics, n (%)

17 (6.5)

49 (20.3)

83 (19.2)

90 (24.1)

< 0.0001

Azithromycin, n (%)

21 (7.9)

29 (12)

50 (11.6)

63 (16.9)

0.0066

Ciclesonide, n (%)

35 (13.3)

48 (19.9)

77 (17.9)

52 (14)

0.0957

Favipiravir, n (%)

29 (10.9)

92 (38)

168 (38.8)

130 (34.8)

< 0.0001

Hydroxychloroquine, n (%)

0 (0)

2 (0.8)

2 (0.5)

2 (0.5)

0.5759

Lopinavir and Ritonavir, n (%)

1 (0.4)

2 (0.8)

0 (0)

2 (0.5)

0.3684

Remdesivir, n (%)

10 (3.8)

53 (22)

85 (19.8)

68 (18.5)

< 0.0001

Nafamostat, n (%)

3 (1.1)

15 (6.2)

39 (9.1)

26 (7.1)

< 0.0001

Anticoagulant, n (%)

15 (5.6)

48 (19.8)

86 (19.9)

98 (26.1)

< 0.0001

Glucocorticoids, n (%)

25 (9.4)

100 (40.8)

219 (50.6)

179 (48)

< 0.0001

  1. Data were compared among groups using χ2 tests