Table 2 Clinical indicators of SPPT and SNPT patients
Normal range | SPPT | SNPT | Control | *Adjusted p-value (SPPT/Ctrl) | *Adjusted p-value (SNPT/Ctrl) | *Adjusted p-value (SPPT/SNPT) | H value (SPPT/SNPT/Ctrl) | p-value (SPPT/SNPT/Ctrl) | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Patients | Median (Q1–Q3) | Patients | Median (Q1–Q3) | Patients | Median (Q1–Q3) | |||||||
Blood routine | ||||||||||||
Leucocytes, × 109/L | 3.5–9.5 | 27 | 7.20 (5.89–8.61) | 37 | 7.65 (6.32–8.74) | 36 | 6.49 (5.66–7.54) | 0.009 | 0.032 | 0.413 | 6.86 | 0.032 |
Neutrophils, × 109/L | 1.8–6.3 | 10 | 7.83 (4.62–11.61) | 37 | 5.10 (3.92–5.94) | 36 | 3.82 (3.18–4.51) | < 0.001 | < 0.001 | 0.068 | 19.6 | < 0.001 |
Erythrocytes, × 1012/L | 4.3–5.8 | 27 | 4.28 (3.88–4.66) | 37 | 4.78 (4.35–4.98) | 36 | 4.77 (4.46–5.25) | < 0.001 | 0.682 | 0.003 | 14.06 | 0.001 |
Hemoglobin, g/L | 130–175 | 27 | 117.00 (104.50–134.00) | 37 | 139.00 (132.00–151.00) | 36 | 140.00 (132.00–151.50) | < 0.001 | 0.961 | < 0.001 | 29.01 | < 0.001 |
Platelets, × 109/L | 125–300 | 26 | 305.50 (238.50–371.75) | 37 | 225.00 (201.00–279.00) | 36 | 265.00 (234.50–348.25) | 0.15 | 0.003 | 0.003 | 10.31 | 0.006 |
Eosinophils, × 109/L | 0.02–0.52 | 27 | 0.12 (0.04–0.34) | 37 | 0.15 (0.10–0.22) | 36 | 0.11 (0.07–0.24) | 0.12 | 0.174 | 0.12 | 0.61 | 0.739 |
Basophils, × 109/L | 0–0.06 | 27 | 0.02 (0.00—0.07) | 37 | 0.02 (0.01–0.05) | 36 | 0.02 (0.01—0.02) | < 0.001 | 0.005 | < 0.001 | 0.73 | 0.693 |
Blood biochemistry | ||||||||||||
Total protein, g/L | 65–85 | 27 | 66.50 (58.75–0.30) | 37 | 66.30 (62.70–68.70) | 34 | 73.40 (70.93–77.18) | < 0.001 | < 0.001 | 0.402 | 31.68 | < 0.001 |
Albumin, g/L | 40–55 | 27 | 35.30 (31.00–38.75) | 37 | 39.20 (36.00–43.00) | 34 | 44.59 (42.73–45.66) | < 0.001 | < 0.001 | 0.002 | 47.21 | < 0.001 |
Globulin, g/L | 20–40 | 16 | 30.65 (26.00–35.75) | 37 | 26.40 (24.00–29.30) | 34 | 28.53 (26.36–32.54) | 0.189 | 0.087 | 0.043 | 7.63 | 0.022 |
Triglyceride, mmol/L | 0.5–1.9 | 25 | 0.99 (0.80–1.22) | 35 | 1.14 (0.89–1.60) | 35 | 1.08 (0.76–1.63) | 0.83 | 0.696 | 0.696 | 1.8 | 0.408 |
Total cholesterol, mmol/L | 2.3–5.2 | 25 | 3.45 (2.87–3.69) | 35 | 3.63 (3.27–4.58) | 35 | 4.15 (3.76–4.98) | < 0.001 | 0.048 | 0.302 | 12.12 | 0.002 |
ASP, IU/L | 9–60 | 27 | 23.00 (18.00–36.50) | 37 | 21.00 (18.00–31.00) | 35 | 19.80 (17.65–22.30) | 0.014 | 0.043 | 0.508 | 3.75 | 0.153 |
ALT, IU/L | 9–50 | 27 | 21.50 (12.55–43.15) | 37 | 19.00 (15.00–29.00) | 35 | 24.20 (15.20–30.40) | 0.269 | 0.269 | 0.586 | 0.51 | 0.776 |
AKP, IU/L | 45–125 | 27 | 68.00 (53.65–102.50) | 37 | 98.00 (74.00–129.00) | 32 | 76.85 (65.80–89.80) | 0.155 | 0.005 | 0.005 | 10.13 | 0.006 |
γ-GT, IU/L | 10–60 | 27 | 33.70 (22.00–55.00) | 37 | 26.00 (20.00–59.00) | 32 | 21.50 (15.75–33.50) | 0.189 | 0.189 | 0.559 | 3.79 | 0.15 |
Creatinine, μmol/L | 57–97 | 27 | 55.20 (44.80–70.70) | 37 | 54.00 (47.00–72.00) | 36 | 65.77 (60.15–74.81) | 0.025 | 0.022 | 0.961 | 7.93 | 0.019 |
Total bilirubin, μmol/L | 0–26 | 27 | 9.60 (7.90–11.85) | 37 | 11.93 (9.20–19.60) | 34 | 12.13 (10.27–13.95) | 0.042 | 0.123 | 0.042 | 6.61 | 0.037 |
Direct bilirubin, μmol/L | 0–8 | 27 | 3.39 (2.30–4.50) | 37 | 2.18 (0.30–3.30) | 6 | 2.31 (2.12–3.82) | 0.421 | < 0.001 | < 0.001 | 6.48 | 0.039 |
Indirect bilirubin, μmol/L | 0–14 | 15 | 6.30 (4.23—8.37) | 37 | 7.90 (6.11–12.15) | 6 | 6.40 (6.20–6.55) | 0.402 | 0.115 | 0.115 | 4.53 | 0.104 |
Inflammatory-related biomarkers | ||||||||||||
ESR, mm/h | 0–15 | 26 | 67.50 (43.75–94.25) | 35 | 43.00 (14.00–62.00) | 0 | – | – | – | 0.003 | – | |
C-reaction protein, mg/L | 0–4 | 27 | 16.53 (9.69–65.08) | 33 | 1.67 (0.80–3.67) | 0 | – | – | – | < 0.001 | – | |
Procalcitonin, ng/mL | 0–0.05 | 15 | 0.10 (0.07–0.36) | 34 | 0.02 (0.01—0.11) | 0 | – | – | – | 0.013 | – | |