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Table 1 Baseline characteristics of SPPT and SNPT patients

From: Combining metabolome and clinical indicators with machine learning provides some promising diagnostic markers to precisely detect smear-positive/negative pulmonary tuberculosis

 

Total (N = 100)

SPPT (N = 27)

SNPT (N = 37)

Control (N = 36)

*Adjusted p-value (SPPT/Ctrl)

*Adjusted p-value (SNPT/Ctrl)

*Adjusted p-value (SPPT/SNPT)

χ2, F or H value (SPPT/SNPT/Ctrl)

p-value (SPPT/SNPT/Ctrl)

Gender (%)

    

0.162

0.43

0.449

4.868$

0.088

 Male

52 (52.0)

18 (66.7)

20 (54.1)

14 (38.9)

     

 Female

48 (48.0)

9 (33.3)

17 (45.9)

22 (61.1)

     

Age (years, median [Q1–Q3])

53.50 (35.00–67.25)

51.00 (32.50–71.00)

60.00 (49.00–71.00)

43.50 (34.00–59.25)

0.087

0.011

0.315

6.369

0.041

Occupations (%)

    

–

–

0.934

–

–

 Farmer

54 (54.0)

23 (85.2)

31 (83.8)

0 (0.0)

     

 Retiree

11 (11.0)

1 (3.7)

1 (2.7)

9 (25.0)

     

 Student

4 (4.0)

1 (3.7)

3 (8.1)

0 (0.0)

     

 Other

6 (6.0)

2 (7.4)

2 (5.4)

2 (5.6)

     

 (Missing value)

25 (25.0)

0 (0.0)

0 (0.0)

25 (69.4)

     

Marital status (%)

    

–

–

0.183

–

–

 Single

7 (7.0)

5 (18.5)

2 (5.4)

0 (0.0)

     

 Married

92 (92.0)

22 (81.5)

35 (94.6)

35 (97.2)

     

 (Missing value)

1 (1.0)

0 (0.0)

0 (0.0)

1 (2.8)

     

BMI (kg/m2, mean[SD])

23.19 (4.44)

20.22 (3.95)

22.82 (3.93)

25.33 (4.13)

< 0.001

0.022

0.027

10.02#

< 0.001

Smoking status (%)

    

–

–

–

–

–

 Never

79 (79.0)

24 (88.9)

34 (91.9)

21 (58.3)

     

 Current

11 (11.0)

3 (11.1)

2 (5.4)

6 (16.7)

     

 Former

1 (1.0)

0 (0.0)

1 (2.7)

0 (0.0)

     

 (Missing value)

9 (9.0)

0 (0.0)

0 (0.0)

9 (25.0)

     

Drinking status (%)

    

–

–

–

–

–

 Never

80 (80.0)

25 (92.6)

37 (100.0)

18 (50.0)

     

 Current

11 (11.0)

2 (7.4)

0 (0.0)

9 (25.0)

     

 Former

1 (1.0)

0 (0.0)

0 (0.0)

1 (2.8)

     

 (Missing value)

8 (8.0)

0 (0.0)

0 (0.0)

8 (22.2)

     

TB contact (%)

    

–

–

< 0.001

–

–

 Yes

44 (68.8)

8 (29.6)

36 (97.3)

–

     

 No

16 (25.0)

16 (59.3)

0 (0.0)

–

     

 (Missing value)

4 (6.3)

3 (11.1)

1 (2.7)

      

TB treatment (%)

    

–

–

0.836

–

–

 New cases of TB

17 (26.6)

7 (25.9)

10 (27.0)

–

     

 Previously treated

41 (64.1)

14 (51.9)

27 (73.0)

–

     

 (Missing value)

6 (9.4)

6 (22.2)

0 (0.0)

      

Cavitary pulmonary TB (%)

33 (51.6)

19 (70.4)

14 (37.8)

–

–

–

0.02

 

–

Symptoms (%)

         

 Cough

60 (92.3)

22 (81.5)

37 (100.0)

–

–

–

0.024

–

–

 Expectoration

60 (92.3)

22 (81.5)

37 (100.0)

–

–

–

0.024

–

–

 Dyspnea

35 (54.7)

6 (22.2)

29 (78.4)

–

–

–

< 0.001

–

–

 Chest discomfort

13 (20.3)

5 (18.5)

8 (21.6)

–

–

–

1

–

–

 Fever

5 (7.8)

3 (11.1)

2 (5.4)

–

–

–

0.713

–

–

 Hemoptysis

2 (3.1)

1 (3.7)

1 (2.7)

–

–

–

1

–

–

 Chest pain

2 (3.1)

1 (3.7)

1 (2.7)

–

–

–

1

–

–

 Nausea

1 (1.6)

0 (0.0)

1 (2.7)

–

–

–

-

–

–

 Fatigue

2 (3.1)

2 (7.4)

0 (0.0)

–

–

–

0.174

–

–

 Night sweats

1 (1.6)

0 (0.0)

1 (2.7)

–

–

–

–

–

–

 Short of breath

3 (4.7)

3 (11.1)

0 (0.0)

–

–

–

–

–

–

  1. BMI body mass index, Data are shown as n (%), mean (SD) or median (Q1–Q3). p-values are calculated after exclusion of missing data for that variable; *Adjusted p-value for multiple comparisons using Bonferroni-Holm correction. SD: standard deviation; (Q1–Q3): 25th Quartile–75th Quartile. $Chi aquare test; #One Way ANOVA;
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BMC Infectious Diseases

ISSN: 1471-2334

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